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1989年小仓纪念讲座:纵隔解剖

1989 Ogura memorial lecture: mediastinal dissection.

作者信息

Sisson G A

机构信息

Department of Otolaryngology-Head and Neck Surgery, Northwestern University Medical School, Chicago, IL 60611.

出版信息

Laryngoscope. 1989 Dec;99(12):1262-6. doi: 10.1288/00005537-198912000-00010.

Abstract

The mediastinal dissection was introduced in 1962 to manage an otherwise uniformly fatal problem in head and neck oncology: stomal recurrence of laryngeal, squamous cell cancer. The morbidity and mortality rates continued to be high and the survival rates low, but they were an improvement over those of other treatment plans. Since then, refinements of the ablative techniques and major advances in the reconstructive techniques have significantly decreased morbidity and mortality rates. The most recent data indicate a 45% survival rate at 42 months. It is evident that early diagnosis and staging of stomal recurrences will yield successful results. Because the mediastinal dissection operation is now safe, it should be applied more liberally in head and neck oncology situations such as subglottic extension of laryngeal cancer, advanced thyroid cancers, cervical esophageal and tracheal cancers, and all head and neck tumors with low-nodal disease.

摘要

纵隔清扫术于1962年被引入,用于处理头颈肿瘤学中一个原本普遍致命的问题:喉鳞状细胞癌的造口复发。其发病率和死亡率持续居高不下,生存率较低,但相较于其他治疗方案已有改善。从那时起,消融技术的改进和重建技术的重大进展显著降低了发病率和死亡率。最新数据显示,42个月时的生存率为45%。显然,造口复发的早期诊断和分期将产生成功的结果。由于纵隔清扫术目前是安全的,因此应更广泛地应用于头颈肿瘤学情况,如喉癌声门下扩展、晚期甲状腺癌、颈段食管癌和气管癌,以及所有伴有低淋巴结转移的头颈肿瘤。

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