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面肌痉挛:20年手术经验及经验教训

Hemifacial spasm: 20-year surgical experience, lesson learned.

作者信息

Soriano-Baron Hector, Vales-Hidalgo Olivia, Arvizu-Saldana Emiliano, Moreno-Jimenez Sergio, Revuelta-Gutierrez Rogelio

机构信息

Division of Neurological Surgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ, U.S.A.

Division of Neurological Surgery, National Institute of Neurology and Neurosurgery, Manuel Velasco Suarez, Mexico City, Mexico.

出版信息

Surg Neurol Int. 2015 May 20;6:83. doi: 10.4103/2152-7806.157443. eCollection 2015.

Abstract

BACKGROUND

Hemifacial spasm is characterized by unilateral, paroxysmal, and involuntary contractions. It is more common in women on the left side. Its evolution is progressive, and it rarely improves without treatment.

METHODS

Microvascular decompressions (N = 226) were performed in 194 Hispanic patients (May 1992-May 2011). Outcomes were evaluated on a 4-point scale: Excellent (complete remission); good (1-2 spasms/day); bad (>2 spasms/day); and recurrence (relapse after initial excellent/good response).

RESULTS

Most patients were female (n = 123); 71 were male. Mean (±SD) age was 49.4 (±11.7) years; age at onset, 43.9 (±11.9) years; time to surgery, 5.7 (±4.7) years. The left side was affected in 114 patients. Typical syndrome occurred in 177 (91.2%); atypical in 17 (8.8%). Findings were primarily vascular compression (n = 185 patients): Anterior inferior cerebellar artery (n = 147), posterior inferior cerebellar artery (n = 12), basilar artery (n = 10), superior cerebellar artery (n = 8), and 2 vessels (n = 8); 9 had no compression. Postsurgical results were primarily excellent (79.9% [n = 155]; good, 4.6% [n = 9]; bad, 15.5% [n = 30]), with recurrence in 21 (10.8%) at mean 51-month (range, 1-133 months) follow-up. Complications included transient hearing loss and facial palsy.

CONCLUSIONS

The anterior inferior cerebellar artery is involved in most cases of hemifacial spasm. Failure to improve postsurgically after 1 week warrants reoperation. Sex, side, and onset are unrelated to treatment response. Microvascular decompression is the preferred treatment. It is minimally invasive, nondestructive, and achieves the best long-term results, with minor morbidity. To our knowledge, this series is the largest to date on a Hispanic population.

摘要

背景

面肌痉挛的特点是单侧、阵发性、不自主收缩。女性左侧更为常见。其病情呈进行性发展,未经治疗很少会改善。

方法

对194名西班牙裔患者(1992年5月至2011年5月)进行了226例微血管减压术。结果采用4分制进行评估:优秀(完全缓解);良好(每天1 - 2次痉挛);差(每天>2次痉挛);复发(最初优秀/良好反应后复发)。

结果

大多数患者为女性(n = 123);71名男性。平均(±标准差)年龄为49.4(±11.7)岁;发病年龄为43.9(±11.9)岁;手术时间为5.7(±4.7)年。114例患者左侧受累。典型综合征发生在177例(91.2%);非典型在17例(8.8%)。主要发现为血管压迫(n = 185例患者):小脑前下动脉(n = 147)、小脑后下动脉(n = 12)、基底动脉(n = 10)、小脑上动脉(n = 8)和2支血管(n = 8);9例无压迫。术后结果主要为优秀(79.9% [n = 155]);良好,4.6% [n = 9];差,15.5% [n = 30]),21例(10.8%)复发,平均随访51个月(范围1 - 133个月)。并发症包括短暂性听力丧失和面神经麻痹。

结论

大多数面肌痉挛病例涉及小脑前下动脉。术后1周未改善值得再次手术。性别、患侧和发病情况与治疗反应无关。微血管减压术是首选治疗方法。它微创、非破坏性,能取得最佳长期效果,且发病率较低。据我们所知,该系列是迄今为止关于西班牙裔人群最大的系列研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0446/4443403/442ac720ad69/SNI-6-83-g001.jpg

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