Alferov V S, Ogol'tsova E S, Kondrat'eva A P
Med Radiol (Mosk). 1989 Dec;34(12):36-9.
As a result of a marked effect of the 1st stage of radiation therapy of 44 patients with stage III (T3N0M0) laryngeal cancer it was followed by therapy after a radical program up to a summary focal dose of 65-70 Gy. Continued tumor growth and recurrences were diagnosed in 19 patients, of them radical operation was performed on 12, 25 patients (57%) have been followed-up for 3 years, without signs of either recurrence or metastases with the preserved larynx. The above results suggest the effectiveness of radiation therapy in locally advanced laryngeal cancer.
44例III期(T3N0M0)喉癌患者在进行第一阶段放射治疗后效果显著,随后按照根治方案继续治疗,直至总局部剂量达到65 - 70 Gy。19例患者被诊断为肿瘤持续生长和复发,其中12例接受了根治性手术,25例患者(57%)进行了3年随访,喉部保留且无复发或转移迹象。上述结果表明放射治疗对局部晚期喉癌有效。