Serkov F N, Gonchar Iu A, Pelevin Iu M
Neirofiziologiia. 1989;21(5):661-7.
Quantity of normal and degenerating axonal terminals (AT) in area 5b of the associative cortex of cat was studied 2, 4 and 30 days after the electrolytic lesion of the thalamic nucleus lateralis posterior (LP). It was established that the quantity of degenerating AT in area 5b two and four days after the LP lesion was 7.4 and 7.2%, respectively. Four days after LP lesions the quantity of normal AT diminished by 16.4%, which was a direct result of excitatory AT degeneration. 40% of vanished AT formed synapses on dendrites and 60%--on spines. The quantity of axosomatic synapses in area 5b did not change after the LP lesion. Consequently, neurons in area 5b receive direct excitatory, predominantly axospinal input from LP. 30 days after LP lesions the total number of AT in area 5b was lower by 100% as compared with the control. Results and peculiarities of reinnervation in area 5b after degeneration of thalamocortical synapses are discussed.
在猫丘脑后外侧核（LP）进行电解损伤后2天、4天和30天，研究了其联合皮层5b区正常和退化轴突终末（AT）的数量。结果发现，LP损伤后2天和4天，5b区退化AT的数量分别为7.4%和7.2%。LP损伤后4天，正常AT的数量减少了16.4%，这是兴奋性AT退化的直接结果。消失的AT中有40%在树突上形成突触，60%在棘上形成突触。LP损伤后，5b区轴体突触的数量没有变化。因此，5b区的神经元接受来自LP的直接兴奋性输入，主要是轴突脊髓输入。与对照组相比，LP损伤后30天，5b区AT的总数减少了100%。本文讨论了丘脑皮质突触退化后5b区再支配的结果和特点。
