[The mechanism of action of pachycarpine on the nicotinic cholinoreceptors of sympathetic ganglion neurons in the rat].
作者信息
Purnyn' S L, Voĭtenko S V
出版信息
Neirofiziologiia. 1989;21(5):701-4.
PMID:2601769
Abstract
The mechanism of the pachycarpine action was studied in isolated superior cervical ganglion of rat using the patch-clamp method in the whole-cell recording mode. Action of the pachycarpine is not potential-dependent in the membrane potential range from +30 to -50 mV, the blockade increases during hyperpolarization of the membrane (-50-90 mV). Changes in the "dose-effect" dependence show that the blocking of nicotinic acetylcholine receptors is competitive both within the potential-dependent interval and within the potential-independent one.
摘要
相似文献
1
[The mechanism of action of pachycarpine on the nicotinic cholinoreceptors of sympathetic ganglion neurons in the rat].
Neirofiziologiia. 1989;21(5):701-4.
2
Effect of (+)-sparteine on nicotinic acetylcholine receptors in the neurons of rat superior cervical ganglion.
Mol Pharmacol. 1991 Aug;40(2):180-5.
3
[The "trap"--a modification of the block of neuronal nicotinic cholinoceptors].
Neirofiziologiia. 1988;20(6):826-9.
4
[Mechanism of action of tubocurarine on nicotinic cholinoreceptors of neurons of the sympathetic ganglia of rats].
Neirofiziologiia. 1988;20(5):672-80.
5
[The potential dependence of acetylcholine-activated membrane conductance in sympathetic ganglion neurons].
Neirofiziologiia. 1988;20(2):167-71.
6
Physostigmine blocked nicotinic acetylcholine receptors in rat sympathetic ganglion neurons.
Zhongguo Yao Li Xue Bao. 1997 Nov;18(6):508-11.
7
[Action of tubocurarine on non-activated nicotinic cholinoreceptors of neurons of sympathetic ganglia in the rat].
Neirofiziologiia. 1989;21(1):130-3.
8
[Activity of single acetylcholine-activated ion channels in the sympathetic neuron].
Dokl Akad Nauk SSSR. 1985;284(2):495-8.
9
[Synaptic effects of nicotinic and muscarinic agonists in the sympathetic ganglia of the frog].
Neirofiziologiia. 1988;20(2):227-34.
10
5-Hydroxytryptamine directly inhibits neuronal nicotinic acetylcholine receptors in rat trigeminal ganglion neurons.
Eur J Pharmacol. 2007 Nov 28;574(2-3):120-6. doi: 10.1016/j.ejphar.2007.07.037. Epub 2007 Jul 28.
Zotero 插件