Tertemiz Kemal Can, Ozgen Alpaydin Aylin, Gurel Duygu, Savas Recep, Gulcu Aytac, Akkoclu Atila
Pulmonary Diseases, Dokuz Eylul University Medical Faculty, Izmir, Turkey.
Pathology, Dokuz Eylul University Medical Faculty, Izmir, Turkey.
Respir Med Case Rep. 2014 Aug 8;13:16-8. doi: 10.1016/j.rmcr.2014.07.003. eCollection 2014.
Malignant pleural mesothelioma (MPM) is a malignant of mesodermal neoplasm and arises from multipotential mesothelial or subserosal cells of the pleura, pericardium and peritoneum.
A seventy five year-old male patient was admitted with chest and lower limb pain. He was a heavy smoker and exposed to environmental asbestos in his childhood. PET-CT scans showed multiple pathological FDG uptakes in lungs and other organs. Biopsies performed from lung and anterior thigh muscles were reported as epitheloid type malignant pleural mesothelioma.
We emphasize that unexpected distant metastases can be observed in MPM and occasionally primary diagnosis can be determined by the biopsy of the metastatic regions. This case also points out the role of PET-CT in the staging of malign mesothelioma by determining different metastatic sites.
恶性胸膜间皮瘤(MPM)是一种中胚层来源的恶性肿瘤,起源于胸膜、心包膜和腹膜的多能间皮细胞或浆膜下细胞。
一名75岁男性患者因胸痛和下肢疼痛入院。他是重度吸烟者,童年时期接触过环境石棉。PET-CT扫描显示肺部和其他器官有多处病理性FDG摄取。肺和大腿前侧肌肉活检报告为上皮样型恶性胸膜间皮瘤。
我们强调,MPM可出现意外的远处转移,偶尔可通过转移部位的活检确定初步诊断。本病例还指出了PET-CT在确定恶性间皮瘤不同转移部位从而进行分期中的作用。