Department of Surgery, "P. Valdoni" - Eleonora Lorrillard, Spencer Cenci Foundation, University "Sapienza" of Rome, Rome, Italy.
Ann Thorac Surg. 2011 Nov;92(5):1898-901. doi: 10.1016/j.athoracsur.2011.04.117. Epub 2011 Oct 31.
We report the case of a 72-year-old woman with metastatic malignant mesothelioma presenting as right colonic polyp. She was diagnosed with malignant pleural mesothelioma 2 years previously and underwent surgery, radiotherapy, and chemotherapy. After 2 years with a negative follow-up, she was admitted to the infectious disease department for malaria and severe anaemia. A computed tomographic scan and a colonoscopy showed a huge bleeding polypoid lesion in the right colon diagnosed as adenocarcinoma. She underwent a right hemicolectomy; a pathologic examination found neoplastic cell population positive to anti-cytokeratin7, anti-calretinin, anti-vimentin, and negative for anti-cytokeratin 20, MOC-31, and thyroid transcription factor 1, providing a diagnosis of metastatic mesothelioma.
我们报告了一例 72 岁女性,患有转移性恶性间皮瘤,表现为右结肠息肉。她在 2 年前被诊断为恶性胸膜间皮瘤,并接受了手术、放疗和化疗。在 2 年的阴性随访后,她因疟疾和严重贫血入住传染病科。计算机断层扫描和结肠镜检查显示右结肠有一个巨大的出血息肉样病变,诊断为腺癌。她接受了右半结肠切除术;病理检查发现肿瘤细胞群体对细胞角蛋白 7、钙视网膜蛋白、波形蛋白呈阳性,对细胞角蛋白 20、MOC-31 和甲状腺转录因子 1 呈阴性,诊断为转移性间皮瘤。