利用源自脐带血（胎儿和新生儿）的自发分裂细胞进行快速染色体分析。

Rapid chromosome analysis with the use of spontaneously dividing cells derived from umbilical cord blood (fetal and neonatal).

作者信息

Tipton R E, Tharapel A T, Chang H H, Simpson J L, Elias S

机构信息

Department of Pediatrics, University of Tennessee, Memphis.

出版信息

Am J Obstet Gynecol. 1989 Dec;161(6 Pt 1):1546-8. doi: 10.1016/0002-9378(89)90923-x.

DOI:10.1016/0002-9378(89)90923-x

PMID:2603909

Abstract

An accurate and reproducible method to obtain high-quality metaphases within 24 hours has been developed. Preparations can be derived from cord blood samples obtained either at delivery or by percutaneous umbilical blood sampling. Mitogens are not required. Rapid cytogenetic analysis can facilitate management of pregnancies characterized by malformations or intrauterine growth retardation.

摘要

已开发出一种在24小时内获得高质量中期分裂相的准确且可重复的方法。制备物可来源于分娩时获得的脐血样本或经皮脐血采样获得的样本。无需有丝分裂原。快速细胞遗传学分析有助于对以畸形或宫内生长迟缓为特征的妊娠进行管理。