Barrera-Bustillos M, Reyes López P A
Instituto Nacional de Cardiología, Ignacio Chávez, México, D.F.
Arch Inst Cardiol Mex. 1989 Sep-Oct;59(5):505-10.
This is a descriptive survey of infectious endocarditis (EI) due to Staphylococci, collected at the Instituto Nacional de Cardiología "Ignacio Chávez", in a ten years period. All had anatomical and bacteriological diagnosis. There were 21 cases, this disease in not rare, and both coagulase-positive or negative Staphylococci were represented in similar proportion as etiologic agents. Coagulase positive organisms produce a clinical picture of septicemia and systemic boxicity, therefore early diagnosis and prompt therapy is forthcoming. Instead coagulase negative EI cause an insidious illness with late diagnosis, focal intramyocardial abscesses and low responsiveness to therapy explain the poor prognosis. It is impossible to differentiate with our present resources between Staphylococcal bacteremia and EI. We recommend, combined antimicrobial therapy and if necessary early surgical treatment.
这是一项对葡萄球菌所致感染性心内膜炎（EI）的描述性调查，数据收集于国立心脏病学研究所“伊格纳西奥·查韦斯”，为期十年。所有病例均有解剖学和细菌学诊断。共有21例，这种疾病并不罕见，凝固酶阳性或阴性葡萄球菌作为病原体的比例相似。凝固酶阳性菌会引发败血症和全身中毒的临床表现，因此能实现早期诊断和及时治疗。相反，凝固酶阴性EI导致隐匿性疾病，诊断较晚，局灶性心肌内脓肿以及对治疗反应性低解释了其预后不良。凭借我们目前的资源，无法区分葡萄球菌菌血症和EI。我们建议采用联合抗菌治疗，必要时进行早期手术治疗。
