Padilla Longoria R, Blanco Benavides R, Peterson Andres J, Juárez Díaz F, Quijano Orvañanos F
Arch Invest Med (Mex). 1989 Apr-Jun;20(2):153-6.
External pancreatic fistulas are secondary to trauma or surgery. Their treatment consists of scrupulous skin care, fluid and electrolyte replacement and nutritional support. Usually they are associated to significant morbidity and mortality as well as long hospital stay. In 1981 Joehl described the inhibitory effect on pancreatic secretion caused by the beta agonist terbutaline, in 1985 he used it successfully in a patient with an external pancreatic fistula following an episode of pancreatitis. We report the case of a 21 year old patient who presented with a 26 day posttraumatic pancreatic fistula that closed five days after the administration of terbutaline. To our knowledge this is the second case reported in the literature. We believe that use of terbutaline, due to its pancreatic inhibitory effect as well as its minimal side effects, might be useful in these patients.
胰外瘘继发于创伤或手术。其治疗包括精心的皮肤护理、液体和电解质补充以及营养支持。通常，它们与显著的发病率和死亡率以及较长的住院时间相关。1981年，乔埃尔描述了β受体激动剂特布他林对胰腺分泌的抑制作用，1985年，他在一名胰腺炎发作后出现胰外瘘的患者中成功使用了该药物。我们报告了一例21岁患者的病例，该患者创伤后胰瘘26天，在使用特布他林五天后瘘口闭合。据我们所知，这是文献中报道的第二例。我们认为，由于特布他林具有胰腺抑制作用且副作用极小，在这些患者中使用可能会有帮助。
