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[人类胚胎期心脏的生长(一项与妊娠第2个月相关的研究)]

[Heart growth in the human embryonic period (a study related to the 2d month of gestation)].

作者信息

Mandarim-de-Lacerda C A

出版信息

Arq Bras Cardiol. 1989 Apr;52(4):185-7.

PMID:2604563
Abstract

The growth of the heart was studied in 27 human staged embryos of post-somitic period (stages from 15 to 23, Carnegie Institution of Washington). The volume of the heart was determined multiplying the cardiac profiles areas (evaluated by point counting planimetry on serial sections) by the thickness of microtomy. Cardiac volume increase was examined relative to age, to crownrump length, and to body weight. The data were transformed into logarithms and bivariate relations were analysed according allometric equations of the form (log y = k log x + log b). The data were fitted according to three techniques: least squares, major axis, and reduced major axis. The slopes of the allometric regressions indicate positive allometry of the cardiac volume relative to embryonic age and to C-R length, and isometry relative to body weight.

摘要

对27个处于体节后时期(华盛顿卡内基研究所的15至23期)的人类分期胚胎的心脏生长情况进行了研究。通过将心脏轮廓面积(通过对连续切片进行点计数平面测量法评估)乘以切片厚度来确定心脏体积。研究了心脏体积相对于年龄、顶臀长度和体重的增加情况。将数据转换为对数,并根据形式为(log y = k log x + log b)的异速生长方程分析二元关系。根据三种技术对数据进行拟合:最小二乘法、主轴法和简约主轴法。异速生长回归的斜率表明,心脏体积相对于胚胎年龄和顶臀长度呈正异速生长,相对于体重呈等速生长。

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