Akgün Mete, Bayrak A Osman, Ozer Bugra, Sağıroğlu M Şamil
Advanced Genomics and Bioinformatics Research Center (İGBAM), Informatics and Information Security Research Center (BİLGEM), The Scientific and Technological Research Council of Turkey (TÜBİTAK), 41470 Gebze, Kocaeli, Turkey.
J Biomed Inform. 2015 Aug;56:103-11. doi: 10.1016/j.jbi.2015.05.022. Epub 2015 Jun 6.
Recently, the rapid advance in genome sequencing technology has led to production of huge amount of sensitive genomic data. However, a serious privacy challenge is confronted with increasing number of genetic tests as genomic data is the ultimate source of identity for humans. Lately, privacy threats and possible solutions regarding the undesired access to genomic data are discussed, however it is challenging to apply proposed solutions to real life problems due to the complex nature of security definitions. In this review, we have categorized pre-existing problems and corresponding solutions in more understandable and convenient way. Additionally, we have also included open privacy problems coming with each genomic data processing procedure. We believe our classification of genome associated privacy problems will pave the way for linking of real-life problems with previously proposed methods.
最近,基因组测序技术的飞速发展导致了大量敏感基因组数据的产生。然而,随着基因检测数量的不断增加,一个严峻的隐私挑战随之而来,因为基因组数据是人类身份的最终来源。最近,人们讨论了关于基因组数据意外访问的隐私威胁及可能的解决方案,然而,由于安全定义的复杂性,将提议的解决方案应用于现实生活问题具有挑战性。在本综述中,我们以更易于理解和方便的方式对先前存在的问题及相应解决方案进行了分类。此外,我们还纳入了每个基因组数据处理过程中出现的开放性隐私问题。我们相信,我们对基因组相关隐私问题的分类将为将现实生活问题与先前提出的方法联系起来铺平道路。