Pruszak Jan
Emmy Noether-Group for Stem Cell Biology, Institute of Anatomy and Cell Biology, University of Freiburg, Albertstr. 17, 79104 Freiburg, Germany.
Mol Cell Ther. 2014 Jan 8;2:2. doi: 10.1186/2052-8426-2-2. eCollection 2014.
For a range of nervous system disorders current treatment options remain limited. Focusing on Parkinson's disease as a neurodegenerative entity that affects an increasing quantity of people in our aging societies, we briefly discuss remaining challenges and opportunities that neural stem cell therapy might be able to offer. Providing a snapshot of neural transplantation paradigms, we contemplate possible imminent translational scenarios and discuss critical requirements to be considered before clinical implementation.
对于一系列神经系统疾病，目前的治疗选择仍然有限。以帕金森病这种在老龄化社会中影响着越来越多人群的神经退行性疾病为例，我们简要讨论神经干细胞疗法可能带来的尚存挑战与机遇。在概述神经移植模式的基础上，我们思考了可能即将出现的转化情况，并讨论了临床实施前需要考虑的关键要求。
