Cormio Luigi, Sanguedolce Francesca, Massenio Paolo, Di Fino Giuseppe, Bruno Mariantonietta, Carrieri Giuseppe
Department of Urology and Renal Transplantation, University of Foggia, Foggia, Italy.
Department of Pathology, University of Foggia, Foggia, Italy.
J Med Case Rep. 2015 Jun 12;9:139. doi: 10.1186/s13256-015-0626-4.
Testicular metastases from pancreatic carcinomas are extremely rare and are usually seen in the late phase of the disease. Fewer than 10 cases have been reported in the literature to date, all of which occurred in patients more than 50 years old. Herein we describe the first case, to our knowledge, of testicular metastasis as the first clinical manifestation of pancreatic carcinoma in a young adult.
A 36-year-old Caucasian man presented to our institution with an acutely developed severe pain in his right testis. His clinical examination and scrotal ultrasounds were consistent with a tumor involving the entire right testis. The patient underwent radical orchiectomy. His pathologic examination revealed the tumor to be a metastasis from a pancreatic cancer that was confirmed by an abdominal computed tomographic scan.
The present case shows that testicular metastasis could be the presenting sign of metastatic pancreatic cancer and that testicular metastases from solid organ tumors, though typical of elderly people, may occasionally be seen in young adults as well.
胰腺癌的睾丸转移极为罕见，通常出现在疾病晚期。迄今为止，文献报道的此类病例不足10例，所有病例均发生在50岁以上的患者中。在此，据我们所知，我们描述了首例年轻成人胰腺癌以睾丸转移作为首发临床表现的病例。
一名36岁的白种男性因突发右侧睾丸剧痛前来我院就诊。他的临床检查和阴囊超声检查结果均显示整个右侧睾丸有肿瘤。患者接受了根治性睾丸切除术。病理检查显示该肿瘤为胰腺癌转移灶，腹部计算机断层扫描证实了这一点。
本病例表明，睾丸转移可能是转移性胰腺癌的首发症状，而且实体器官肿瘤的睾丸转移虽然多见于老年人，但偶尔也可见于年轻成人。
