医学桂冠上的羽毛
Feather on the Cap of Medicine.
作者信息
Chiu Cathleen Tsz Ka, Chuong Cheng Ming
机构信息
Department of Pathology, University of Southern California, Los Angeles, California, USA.
Department of Pathology, University of Southern California, Los Angeles, California, USA; Research Center for Developmental Biology and Regenerative Medicine, National Taiwan University, Taipei, Taiwan; Laboratory for Wound Repair and Regeneration, Cheng Kung University, Tainan, Taiwan; Integrative Evolutionary Galliform Genomics Center, Chung-Hsing University. Taichung, Taiwan.
出版信息
J Invest Dermatol. 2015 Jul;135(7):1719-1721. doi: 10.1038/jid.2015.2.
Through cyclic regeneration, feather stem cells are molded into different shapes under different physiological states. With its distinct morphology, context-dependent growth, and experimental manipulability, the feather provides a rich model to study growth control, regeneration, and morphogenesis in vivo. Recent examples include novel insights revealed by transient perturbation with chemotherapeutic reagents and irradiation during feather growth.
通过循环再生，羽毛干细胞在不同生理状态下被塑造成不同形状。凭借其独特的形态、依赖环境的生长以及实验可操作性，羽毛为研究体内生长控制、再生和形态发生提供了丰富的模型。最近的例子包括在羽毛生长过程中用化疗试剂和辐射进行短暂扰动所揭示的新见解。
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