Mehta M N, Joseph L J, Desai K B
Radiation Medicine Centre, Bhabha Atomic Research Centre, Bombay, India.
Int J Rad Appl Instrum B. 1989;16(6):599-601. doi: 10.1016/0883-2897(89)90076-7.
Simultaneous production of antibodies against triiodothyronine and thyroxine was attempted in a single rabbit by immunizing the animal with T3-albumin conjugate and T4-albumin conjugate at the same time. This resulted in the production of antibodies against both T3 and T4. The characteristics of each antibody were studied and the antiserum was used for determination of serum T3 and T4 concentrations by radioimmunoassay. The results were compared with those obtained with antibodies against T3 and T4 which were produced individually in different rabbits and were found to be more or less similar. From the results of the experiments, it appears that it is possible to make antibodies against T3 and T4 simultaneously in a single rabbit.
通过同时用三碘甲状腺原氨酸（T3）-白蛋白偶联物和甲状腺素（T4）-白蛋白偶联物免疫一只兔子，尝试在该兔子体内同时产生针对T3和T4的抗体。这导致产生了针对T3和T4的抗体。研究了每种抗体的特性，并将抗血清用于通过放射免疫测定法测定血清T3和T4浓度。将结果与在不同兔子中单独产生的针对T3和T4的抗体所获得的结果进行比较，发现大致相似。从实验结果来看，似乎有可能在一只兔子体内同时产生针对T3和T4的抗体。
