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多囊卵巢综合征女性体外受精或卵胞浆内单精子注射前及期间使用二甲双胍治疗:Cochrane系统评价总结

Metformin treatment before and during in vitro fertilization or intracytoplasmic sperm injection in women with polycystic ovary syndrome: summary of a Cochrane review.

作者信息

Tso Leopoldo O, Costello Michael F, Albuquerque Luiz Eduardo T, Andriolo Régis B, Marjoribanks Jane, Macedo Cristiane R

机构信息

Department of Gynecology, Federal University of São Paulo, São Paulo, Brazil.

Division of Obstetrics & Gynaecology, School of Women's and Children's Health, University of New South Wales and Royal Hospital for Women and IVF Australia, Sydney, New South Wales, Australia.

出版信息

Fertil Steril. 2015 Sep;104(3):542-4. doi: 10.1016/j.fertnstert.2015.05.038. Epub 2015 Jun 24.

DOI:10.1016/j.fertnstert.2015.05.038
PMID:26070519
Abstract

In women with polycystic ovary syndrome, metformin treatment before or during assisted reproductive technology cycles increases clinical pregnancy rates and decreases the risk of ovarian hyperstimulation syndrome. However, there is no conclusive evidence of a benefit in live birth rates.

摘要

在多囊卵巢综合征女性中,在辅助生殖技术周期之前或期间使用二甲双胍治疗可提高临床妊娠率,并降低卵巢过度刺激综合征的风险。然而,尚无确凿证据表明其对活产率有益。

相似文献

1
Metformin treatment before and during in vitro fertilization or intracytoplasmic sperm injection in women with polycystic ovary syndrome: summary of a Cochrane review.多囊卵巢综合征女性体外受精或卵胞浆内单精子注射前及期间使用二甲双胍治疗:Cochrane系统评价总结
Fertil Steril. 2015 Sep;104(3):542-4. doi: 10.1016/j.fertnstert.2015.05.038. Epub 2015 Jun 24.
2
Effects of metformin in women with polycystic ovary syndrome treated with gonadotrophins for in vitro fertilisation and intracytoplasmic sperm injection cycles: a systematic review and meta-analysis of randomised controlled trials.二甲双胍对接受促性腺激素治疗的多囊卵巢综合征患者体外受精和胞浆内单精子注射周期的影响:一项随机对照试验的系统评价和荟萃分析。
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3
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Fertil Steril. 2011 Nov;96(5):1128-33. doi: 10.1016/j.fertnstert.2011.08.020. Epub 2011 Sep 13.
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Metformin reduces risk of ovarian hyperstimulation syndrome in patients with polycystic ovary syndrome during gonadotropin-stimulated in vitro fertilization cycles: a randomized, controlled trial.二甲双胍可降低多囊卵巢综合征患者在促性腺激素刺激体外受精周期中发生卵巢过度刺激综合征的风险:一项随机对照试验。
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引用本文的文献

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A Review of Second- and Third-line Infertility Treatments and Supporting Evidence in Women with Polycystic Ovary Syndrome.多囊卵巢综合征女性二线和三线不孕症治疗及支持证据综述
Med Sci (Basel). 2019 Jun 26;7(7):75. doi: 10.3390/medsci7070075.
2
Metformin in Reproductive Biology.二甲双胍在生殖生物学中的应用
Front Endocrinol (Lausanne). 2018 Nov 22;9:675. doi: 10.3389/fendo.2018.00675. eCollection 2018.
3
A healthy HLA-matched baby born by using a combination of aCGH and Karyomapping: the first latin american case.通过综合运用比较基因组杂交(aCGH)和核型定位技术诞生的一名健康的 HLA 匹配婴儿:首例拉丁美洲病例。
JBRA Assist Reprod. 2017 Dec 1;21(4):370-375. doi: 10.5935/1518-0557.20170063.
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Effect of metformin and oral contraceptives on polycystic ovary syndrome and IVF cycles.二甲双胍和口服避孕药对多囊卵巢综合征和 IVF 周期的影响。
J Endocrinol Invest. 2017 Jul;40(7):745-752. doi: 10.1007/s40618-017-0634-x. Epub 2017 Feb 27.
5
Insulin signalling and glucose transport in the ovary and ovarian function during the ovarian cycle.卵巢周期中卵巢内的胰岛素信号传导、葡萄糖转运与卵巢功能
Biochem J. 2016 Jun 1;473(11):1483-501. doi: 10.1042/BCJ20160124.