宫颈癌孤立性颅骨转移患者的长期生存——病例报告及文献复习

Zilberlicht Ariel, Voldavsky Eugene, Lavie Ofer, Auslender Ron, Shai Ayelet

Department of Obstetrics and Gynecology, The Lady Davis Carmel Medical Center, Haifa 34362, Israel.

Pathology Institute, Rambam Health Care Campus, Haifa, Israel.

Gynecol Oncol Rep. 2014 Dec 24;11:20-2. doi: 10.1016/j.gore.2014.12.002. eCollection 2015 Jan.

A 58 years old woman was diagnosed with squamous cell carcinoma of the uterine cervix FIGO stage IIB and was treated by concomitant radio-chemotherapy followed by simple hysterectomy. Several months later a single metastasis to the skull was diagnosed. The patient underwent craniotomy and radiotherapy and achieved a prolonged disease free survival of 20 months. Bone metastases from cervical carcinoma are usually part of widespread metastatic disease. Skull metastases are extremely rare. Selected cases of solitary bone metastases can be treated radically and achieve long term disease free survival.

一名58岁女性被诊断为子宫颈鳞状细胞癌，国际妇产科联盟（FIGO）分期为IIB期，接受了同步放化疗，随后进行了单纯子宫切除术。几个月后，诊断出颅骨有单个转移灶。患者接受了开颅手术和放疗，实现了20个月的长期无病生存。宫颈癌的骨转移通常是广泛转移性疾病的一部分。颅骨转移极为罕见。部分孤立性骨转移病例可进行根治性治疗并实现长期无病生存。