• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

宫颈癌孤立性颅骨转移患者的长期生存——病例报告及文献复习

Prolonged survival in a patient with isolated skull recurrence of cervical carcinoma - Case report and review of the literature.

作者信息

Zilberlicht Ariel, Voldavsky Eugene, Lavie Ofer, Auslender Ron, Shai Ayelet

机构信息

Department of Obstetrics and Gynecology, The Lady Davis Carmel Medical Center, Haifa 34362, Israel.

Pathology Institute, Rambam Health Care Campus, Haifa, Israel.

出版信息

Gynecol Oncol Rep. 2014 Dec 24;11:20-2. doi: 10.1016/j.gore.2014.12.002. eCollection 2015 Jan.

DOI:10.1016/j.gore.2014.12.002
PMID:26076088
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4434164/
Abstract

A 58 years old woman was diagnosed with squamous cell carcinoma of the uterine cervix FIGO stage IIB and was treated by concomitant radio-chemotherapy followed by simple hysterectomy. Several months later a single metastasis to the skull was diagnosed. The patient underwent craniotomy and radiotherapy and achieved a prolonged disease free survival of 20 months. Bone metastases from cervical carcinoma are usually part of widespread metastatic disease. Skull metastases are extremely rare. Selected cases of solitary bone metastases can be treated radically and achieve long term disease free survival.

摘要

一名58岁女性被诊断为子宫颈鳞状细胞癌,国际妇产科联盟(FIGO)分期为IIB期,接受了同步放化疗,随后进行了单纯子宫切除术。几个月后,诊断出颅骨有单个转移灶。患者接受了开颅手术和放疗,实现了20个月的长期无病生存。宫颈癌的骨转移通常是广泛转移性疾病的一部分。颅骨转移极为罕见。部分孤立性骨转移病例可进行根治性治疗并实现长期无病生存。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5526/4434164/8b1edb65bab7/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5526/4434164/ab0ec0ba04fa/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5526/4434164/8b1edb65bab7/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5526/4434164/ab0ec0ba04fa/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5526/4434164/8b1edb65bab7/gr2.jpg

相似文献

1
Prolonged survival in a patient with isolated skull recurrence of cervical carcinoma - Case report and review of the literature.宫颈癌孤立性颅骨转移患者的长期生存——病例报告及文献复习
Gynecol Oncol Rep. 2014 Dec 24;11:20-2. doi: 10.1016/j.gore.2014.12.002. eCollection 2015 Jan.
2
[Analysis of prognostic factors and therapeutic patterns of recurrent stage Ⅰb-Ⅱa cervical squamous carcinoma treated with radical hysterectomy].[根治性子宫切除术治疗复发性Ⅰb-Ⅱa期宫颈鳞癌的预后因素及治疗模式分析]
Zhonghua Fu Chan Ke Za Zhi. 2019 Jun 25;54(6):399-405. doi: 10.3760/cma.j.issn.0529-567x.2019.06.008.
3
[Clinical analysis of 32 cases with neuroendocrine carcinoma of the uterine cervix in early-stage disease].32例早期子宫颈神经内分泌癌临床分析
Zhonghua Fu Chan Ke Za Zhi. 2015 Mar;50(3):198-203.
4
Scalp metastasis in carcinoma of the uterine cervix--a rare entity.子宫颈癌的头皮转移——一种罕见情况。
Gynecol Oncol. 2002 Dec;87(3):310-2. doi: 10.1006/gyno.2002.6829.
5
[Significance and implication on changes of serum squamous cell carcinoma antigen in the diagnosis of recurrence squamous cell carcinoma of cervix].[血清鳞状细胞癌抗原变化在宫颈复发鳞状细胞癌诊断中的意义及启示]
Zhonghua Fu Chan Ke Za Zhi. 2015 Feb;50(2):131-6.
6
Carcinoma of uterine cervix with isolated metastasis to fibula and its unusual behavior: report of a case and review of literature.子宫颈癌孤立转移至腓骨及其异常表现:1例报告并文献复习
J Cancer Res Ther. 2006 Apr-Jun;2(2):79-81. doi: 10.4103/0973-1482.25857.
7
[Outcomes and prognostic factors of distant metastasis in patients with advanced cervical squamous cell carcinoma treated with concurrent chemoradiotherapy].[同步放化疗治疗晚期宫颈鳞状细胞癌患者远处转移的结局及预后因素]
Zhonghua Fu Chan Ke Za Zhi. 2015 Feb;50(2):125-30.
8
Hyperfractionated radiotherapy with concurrent chemotherapy for para-aortic lymph node recurrence in carcinoma of the cervix.超分割放疗联合化疗治疗宫颈癌腹主动脉旁淋巴结复发
Int J Radiat Oncol Biol Phys. 2003 Apr 1;55(5):1247-53. doi: 10.1016/s0360-3016(02)04401-2.
9
Overexpression of cyclooxygenase-2 is associated with a poor prognosis in patients with squamous cell carcinoma of the uterine cervix treated with radiation and concurrent chemotherapy.在接受放疗和同步化疗的子宫颈鳞状细胞癌患者中,环氧合酶-2的过表达与预后不良相关。
Cancer. 2002 Aug 1;95(3):531-9. doi: 10.1002/cncr.10684.
10
Role of metastasectomy and chemotherapy in carcinoma of uterine cervix.子宫颈癌中转移灶切除术及化疗的作用
BMJ Case Rep. 2017 Aug 2;2017:bcr-2017-221153. doi: 10.1136/bcr-2017-221153.

引用本文的文献

1
Skull Oligometastasis From Cervical Cancer: A Case Report.宫颈癌颅骨寡转移:一例报告
Cureus. 2025 Jan 28;17(1):e78115. doi: 10.7759/cureus.78115. eCollection 2025 Jan.
2
Solitary skull metastasis in presumed early stage cervical cancer.疑似早期宫颈癌的孤立性颅骨转移
Gynecol Oncol Rep. 2021 Nov 13;38:100889. doi: 10.1016/j.gore.2021.100889. eCollection 2021 Nov.

本文引用的文献

1
Improved survival with bevacizumab in advanced cervical cancer.贝伐珠单抗治疗晚期宫颈癌可提高生存率。
N Engl J Med. 2014 Feb 20;370(8):734-43. doi: 10.1056/NEJMoa1309748.
2
Skull metastasis from carcinoma of the cervix: a rare case and review of the literature.宫颈癌颅骨转移:1例罕见病例及文献复习
J Obstet Gynaecol Res. 2010 Apr;36(2):441-3. doi: 10.1111/j.1447-0756.2009.01139.x.
3
Bulky scalp metastasis and superior sagittal sinus thrombosis from a cervical adenocarcinoma: an unusual case.一例罕见的宫颈腺癌导致的巨大头皮转移瘤及上矢状窦血栓形成病例
J Med Imaging Radiat Oncol. 2008 Feb;52(1):91-4. doi: 10.1111/j.1440-1673.2007.01918.x.
4
Carcinoma of uterine cervix with isolated metastasis to fibula and its unusual behavior: report of a case and review of literature.子宫颈癌孤立转移至腓骨及其异常表现:1例报告并文献复习
J Cancer Res Ther. 2006 Apr-Jun;2(2):79-81. doi: 10.4103/0973-1482.25857.
5
Cervix carcinoma, concurrent chemoradiotherapy, and salvage of isolated paraaortic lymph node recurrence.宫颈癌、同步放化疗及孤立性主动脉旁淋巴结复发的挽救治疗
Int J Radiat Oncol Biol Phys. 2005 Feb 1;61(2):450-5. doi: 10.1016/j.ijrobp.2004.06.207.
6
Pulmonary metastases from uterine malignancies: results of surgical resection in 133 patients.子宫恶性肿瘤的肺转移:133例手术切除结果
J Thorac Cardiovasc Surg. 2004 Apr;127(4):1107-12. doi: 10.1016/j.jtcvs.2003.10.011.
7
Scalp metastasis in carcinoma of the uterine cervix--a rare entity.子宫颈癌的头皮转移——一种罕见情况。
Gynecol Oncol. 2002 Dec;87(3):310-2. doi: 10.1006/gyno.2002.6829.
8
Pulmonary resection in metastatic uterine and cervical malignancies.转移性子宫和宫颈恶性肿瘤的肺切除术
Gynecol Oncol. 2001 Dec;83(3):472-6. doi: 10.1006/gyno.2001.6427.
9
Isolated paraaortic lymph node recurrence after definitive irradiation for cervical carcinoma.宫颈癌根治性放疗后孤立性腹主动脉旁淋巴结复发。
Int J Radiat Oncol Biol Phys. 2001 Oct 1;51(2):442-8. doi: 10.1016/s0360-3016(01)01628-5.
10
Distant metastases in squamous-cell carcinoma of the uterine cervix.子宫颈鳞状细胞癌的远处转移
Radiology. 1967 May;88(5):961-6. doi: 10.1148/88.5.961.