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在一名晚期喉癌患者中使用异种脱细胞真皮基质修复颈部皮肤缺损。

Repair of a cervical skin defect using xenogeneic acellular dermal matrix in a patient with advanced laryngeal carcinoma.

作者信息

Wang L, Li L, Lou W

机构信息

Department of Otolaryngology - Head and Neck Surgery,First Affiliated Hospital,Zhengzhou University,China.

Department of Otolaryngology Head and Neck Surgery,Beijing Tongren Hospital,Capital Medical University,China.

出版信息

J Laryngol Otol. 2015 Jul;129(7):715-7. doi: 10.1017/S0022215115001413. Epub 2015 Jun 17.

Abstract

OBJECTIVE

This paper reports the outcome of using acellular dermal matrix to repair a cervical skin defect in a patient with an advanced laryngeal carcinoma that had invaded the skin.

CASE REPORT

A 55-year-old man underwent surgical repair of severe atypical hyperplasia and of a squamous cell carcinoma at 17 and 9 months, respectively, prior to undergoing the current procedure. Five months prior to the current procedure, his left cervical skin broke down and the lesion gradually enlarged. A pathological diagnosis of squamous cell carcinoma was made. The cervical skin defect was repaired with a tailored acellular dermal matrix patch. The cervical wound completely healed without developing infection or a pharyngeal fistula, and the patient exhibited no dysphagia three years after surgery.

CONCLUSION

Cervical skin defects can be successfully repaired with acellular dermal matrix.

摘要

目的

本文报告了使用脱细胞真皮基质修复一名晚期喉癌侵犯皮肤患者颈部皮肤缺损的结果。

病例报告

一名55岁男性在进行本次手术前,分别于17个月和9个月时接受了严重非典型增生和鳞状细胞癌的手术修复。在本次手术前5个月,他的左颈部皮肤破溃,病变逐渐扩大。病理诊断为鳞状细胞癌。使用定制的脱细胞真皮基质补片修复颈部皮肤缺损。颈部伤口完全愈合,未发生感染或咽瘘,术后三年患者无吞咽困难。

结论

脱细胞真皮基质可成功修复颈部皮肤缺损。

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