Narula Neha G, Abril Andy
Department of Rheumatology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.
Clin Rheumatol. 2016 Mar;35(3):807-12. doi: 10.1007/s10067-015-2993-z. Epub 2015 Jun 18.
A number of autoimmune disorders, such as large vessel vasculitis, have been recognized in patients who have myelodysplastic syndrome (MDS) and myeloproliferative syndrome (MPS). The influence of an autoimmune disorder on the prognosis of patients who have MDS and MPS remains to be determined. We report three cases of myelodysplastic syndrome and large vessel vasculitis seen at our institution and provide a brief literature review of the two disease processes. More studies are needed to determine the pathophysiology of the underlying diseases and whether there truly is a relationship between the disease entities and to discover better markers for disease assessment.
在骨髓增生异常综合征（MDS）和骨髓增殖性综合征（MPS）患者中，已发现多种自身免疫性疾病，如大血管血管炎。自身免疫性疾病对MDS和MPS患者预后的影响尚待确定。我们报告了在本机构所见的3例骨髓增生异常综合征合并大血管血管炎病例，并对这两种疾病过程进行简要文献综述。需要更多研究来确定潜在疾病的病理生理学，以及这两种疾病实体之间是否真的存在关联，并发现更好的疾病评估标志物。
