Chen Xiao-xian, Lin Bi-chen, Zhong Jie, Ge Li-hong
Department of Pediatric Dentistry, First Dental Center, Peking University School and Hospital of Stomatology, Beijing 100034, China.
Department of Pediatric Dentistry, Peking University School and Hospital of Stomatology, Beijing 100081, China.
Beijing Da Xue Xue Bao Yi Xue Ban. 2015 Jun 18;47(3):529-35.
To compare clinical and radiographic success rates of a modified primary root canal filling (ingredients: zinc oxide-eugenol, iodoform and calcium hydroxide, MPRCF) vs. zinc oxide-eugenol cement (ZOE) and calcium hydroxide/iodoform paste (Vitapex) in pulpectomized primary molars at the end of 6 and 12 months, and to evaluate the degradation of materials in the root canals and in apical area.
In the study, 160 primary molars from 155 children (the average age: 5.88±1.27 years) that met the inclusion criteria were allocated to one of the three materials via block randomization. A two-visit pulpectomy was performed by an investigator. The clinical and radiographic diagnoses were blindly assessed by other two investigators.
At the end of 6 and 12 months, the ZOE and MPRCF success rates were 100% both in clinical and radiographic evaluation. The Vitapex group showed the clinical success of 100% at the end of 6 months and 94.5% at the end of 12 months. Radiographic evaluation for the Vitapex group showed 80.4% success at the end of 6 months and 60.7% at the end of 12 months. No statistically significant differences were noted at the end of 6 months in the three groups both in clinical and radiographic evaluation. The success rates in clinical and radiographic evaluation at the end of 12 months for ZOE and MPRCF groups were not significantly different, and better than those for Vitapex group with statistically significant difference. The completely resorb rate of excess extruded extraradicularly were 14.3%, 100% and 71.4% for ZOE, Vitapex and MPRCF at the end of 12 months. The rates of resorption of material at the same rate of the root were 5.8%, 7.2% and 40.9% for ZOE, Vitapex and MPRCF at the end of 12 months.
MPRCF, a mixture of zinc oxide eugenol and iodoform with calcium hydroxide can be used as a root canal filling material in primary teeth, taking account of the success rate and resorbing at a similar rate with the roots of the primary teeth.
比较改良型乳牙根管充填材料（成分：氧化锌丁香酚、碘仿和氢氧化钙，MPRCF）与氧化锌丁香酚水门汀（ZOE）和氢氧化钙/碘仿糊剂（Vitapex）在乳牙牙髓摘除术后6个月和12个月时的临床和影像学成功率，并评估根管及根尖区材料的降解情况。
本研究中，将符合纳入标准的155名儿童的160颗乳牙通过区组随机化分配至三种材料组之一。由一名研究者进行两次就诊的牙髓摘除术。由另外两名研究者对临床和影像学诊断进行盲法评估。
在6个月和12个月时，ZOE和MPRCF在临床和影像学评估中的成功率均为100%。Vitapex组在6个月时临床成功率为100%，12个月时为94.5%。Vitapex组的影像学评估显示，6个月时成功率为80.4%，12个月时为60.7%。在6个月时，三组在临床和影像学评估中均未观察到统计学显著差异。ZOE组和MPRCF组在12个月时的临床和影像学评估成功率无显著差异，且优于Vitapex组，差异具有统计学意义。在12个月时，ZOE、Vitapex和MPRCF超出根尖孔外的材料完全吸收率分别为14.3%、100%和71.4%。在12个月时，ZOE、Vitapex和MPRCF在牙根相同吸收速率下材料的吸收速率分别为5.8%、7.2%和40.9%。
考虑到成功率以及与乳牙牙根以相似速率吸收，由氧化锌丁香酚、碘仿和氢氧化钙混合而成的MPRCF可作为乳牙根管充填材料。
