GM-CSF 体外生成树突状细胞的讣告？
A Death Notice for In-Vitro-Generated GM-CSF Dendritic Cells?
机构信息
Laboratory of Immunoregulation, VIB Inflammation Research Center, 9000 Ghent, Belgium.
Centre d'Immunologie de Marseille-Luminy, UM2 Aix Marseille Université, INSERM, U1104, CNRS UMR7280, 13288 Marseille, France.
出版信息
Immunity. 2015 Jun 16;42(6):988-90. doi: 10.1016/j.immuni.2015.05.020.
PMID:26084019
Abstract
Mouse bone marrow cells cultured with GM-CSF are often used to generate dendritic cells (DCs); in this issue of Immunity, Helft et al. (2015) show that this classical method produces heterogeneous populations of myeloid cells that are only distantly related to macrophages and DCs found in vivo.
摘要
用 GM-CSF 培养的小鼠骨髓细胞常用于生成树突状细胞 (DCs)；在本期《免疫》中，Helft 等人（2015 年）表明，这种经典方法产生的髓系细胞群体存在异质性，与体内存在的巨噬细胞和 DCs 关系疏远。
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