Bramley P N, Shah P, Williams D J, Losowsky M S
Department of Medicine, St. James's University Hospital, Leeds, UK.
Postgrad Med J. 1989 Sep;65(767):687-8. doi: 10.1136/pgmj.65.767.687.
A previously fit 56 year old female presented with a rapidly progressive and fatal pneumococcal septicaemia with disseminated intravascular coagulation. Post-mortem studies confirmed a Waterhouse-Friderichsen syndrome and revealed an anatomically normal spleen; intracellular diplococci were seen within splenic macrophages providing evidence of normal splenic function. This appears to be only the second case of Waterhouse-Friderichsen syndrome due to pneumococcal septicaemia in a patient with a normal spleen.
一名56岁既往健康的女性，因肺炎球菌败血症合并弥散性血管内凝血，病情迅速进展并最终死亡。尸检证实为华-佛综合征，脾脏解剖结构正常；在脾巨噬细胞内可见细胞内双球菌，提示脾脏功能正常。这似乎是第二例脾脏正常的患者因肺炎球菌败血症导致华-佛综合征的病例。
