Reineke Erica L, Rees Colleen, Drobatz Kenneth J
J Am Vet Med Assoc. 2015 Jul 1;247(1):79-84. doi: 10.2460/javma.247.1.79.
To determine the association of blood lactate concentration with physically assessed perfusion variables, systolic arterial blood pressure (SAP), and outcome in cats evaluated by an emergency service.
Prospective, observational study.
111 cats.
Initial blood lactate concentration and SAP (prior to any therapeutic interventions) as well as physically assessed perfusion variables (mucous membrane color, capillary refill time, peripheral pulse quality, heart rate, and rectal temperature) were determined. Cats were categorized as having no shock, mild to moderate shock, or severe shock. Outcomes were recorded. Associations between lactate concentration and these variables were assessed.
Median initial blood lactate concentration was 2.7 mmol/L (range, 0.5 to 19.3 mmol/L); cats with white mucous membranes, abnormal peripheral pulse quality, and hypothermia had significantly higher lactate concentration than did cats without these findings. Median lactate concentration for cats with SAP < 90 mm Hg (3.3 mmol/L) was significantly higher than that of cats with SAP ≥ 90 mm Hg (2.35 mmol/L). Cats with severe shock had significantly higher lactate concentration (4.3 mmol/L) than did cats in other shock categories. Median initial lactate concentration at admission did not differ between cats that did (2.45 mmol/L) and did not (3.2 mmol/L) survive to discharge from the hospital. Change in lactate concentration during hospitalization (when applicable) was not associated with outcome.
Findings indicated that blood lactate concentration, together with physical examination findings and SAP, may be a useful tool for identifying abnormalities in tissue oxygen delivery in cats. However, lactate concentrations were not associated with outcome in the present study.
确定在由急诊服务评估的猫中，血乳酸浓度与体格检查评估的灌注变量、收缩期动脉血压（SAP）及预后之间的关联。
前瞻性观察性研究。
111只猫。
测定初始血乳酸浓度和SAP（在任何治疗干预之前）以及体格检查评估的灌注变量（黏膜颜色、毛细血管再充盈时间、外周脉搏质量、心率和直肠温度）。将猫分为无休克、轻度至中度休克或重度休克。记录预后情况。评估乳酸浓度与这些变量之间的关联。
初始血乳酸浓度中位数为2.7 mmol/L（范围为0.5至19.3 mmol/L）；黏膜呈白色、外周脉搏质量异常和体温过低的猫，其乳酸浓度显著高于无这些表现的猫。SAP < 90 mmHg的猫的乳酸浓度中位数（3.3 mmol/L）显著高于SAP≥90 mmHg的猫（2.35 mmol/L）。重度休克的猫的乳酸浓度（4.3 mmol/L）显著高于其他休克类型的猫。入院时初始乳酸浓度中位数在存活至出院的猫（2.45 mmol/L）和未存活至出院的猫（3.2 mmol/L）之间无差异。住院期间（如适用）乳酸浓度的变化与预后无关。
研究结果表明，血乳酸浓度连同体格检查结果和SAP，可能是识别猫组织氧输送异常的有用工具。然而，在本研究中乳酸浓度与预后无关。
