McCluggage W Glenn, Judge Meagan J, Clarke Blaise A, Davidson Ben, Gilks C Blake, Hollema Harry, Ledermann Jonathan A, Matias-Guiu Xavier, Mikami Yoshiki, Stewart Colin J R, Vang Russell, Hirschowitz Lynn
Department of Pathology, Belfast Health and Social Care Trust, Belfast, UK.
Royal College of Pathologists of Australasia, Sydney, NSW, Australia.
Mod Pathol. 2015 Aug;28(8):1101-22. doi: 10.1038/modpathol.2015.77. Epub 2015 Jun 19.
A comprehensive pathological report is essential for optimal patient management, cancer staging and prognostication. In many countries, proforma reports are used but these vary in their content. The International Collaboration on Cancer Reporting (ICCR) is an alliance formed by the Royal College of Pathologists of Australasia, the Royal College of Pathologists of the United Kingdom, the College of American Pathologists, the Canadian Partnership Against Cancer and the European Society of Pathology, with the aim of developing an evidence-based reporting data set for each cancer site. This will reduce the global burden of cancer data set development and reduplication of effort by different international institutions that commission, publish and maintain standardised cancer reporting data sets. The resultant standardisation of cancer reporting will benefit not only those countries directly involved in the collaboration but also others not in a position to develop their own data sets. We describe the development of a cancer data set by the ICCR expert panel for the reporting of primary ovarian, fallopian tube and peritoneal carcinoma and present the 'required' and 'recommended' elements to be included in the report with an explanatory commentary. This data set encompasses the recent International Federation of Obstetricians and Gynaecologists staging system for these neoplasms and the updated World Health Organisation Classification of Tumours of the Female Reproductive Organs. The data set also addresses issues about site assignment of the primary tumour in high-grade serous carcinomas and proposes a scoring system for the assessment of tumour response to neoadjuvant chemotherapy. The widespread implementation of this data set will facilitate consistent and accurate data collection, comparison of epidemiological and pathological parameters between different populations, facilitate research and hopefully will result in improved patient management.
一份全面的病理报告对于患者的最佳管理、癌症分期和预后判断至关重要。在许多国家，使用的是格式化报告，但这些报告的内容各不相同。国际癌症报告协作组织（ICCR）是由澳大利亚皇家病理学家学院、英国皇家病理学家学院、美国病理学家学会、加拿大抗癌伙伴组织和欧洲病理学会组成的联盟，其目的是为每个癌症部位制定一个基于证据的报告数据集。这将减轻全球癌症数据集开发的负担，并减少不同国际机构在委托、发布和维护标准化癌症报告数据集方面的重复工作。由此产生的癌症报告标准化不仅将使直接参与合作的国家受益，也将使那些无法自行开发数据集的国家受益。我们描述了ICCR专家小组为原发性卵巢癌、输卵管癌和腹膜癌报告制定癌症数据集的过程，并给出报告中应包含的“必需”和“推荐”要素以及解释性说明。该数据集涵盖了国际妇产科联合会针对这些肿瘤的最新分期系统以及世界卫生组织更新后的女性生殖器官肿瘤分类。该数据集还解决了高级别浆液性癌中原发性肿瘤部位分配的问题，并提出了一个评估肿瘤对新辅助化疗反应的评分系统。广泛实施这个数据集将有助于进行一致且准确的数据收集，便于比较不同人群之间的流行病学和病理参数，促进研究，并有望改善患者管理。
