Bignami Elena, Belletti Alessandro, Moliterni Paola, Frati Elena, Guarnieri Marcello, Tritapepe Luigi
Department of Anesthesia and Intensive Care, San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.
Department of Cardiovascular Sciences, Centro Cardiologico Monzino, IRCCS, University of Milan, Via Carlo Parea 4, 20138, Milan, Italy.
J Clin Monit Comput. 2016 Jun;30(3):347-65. doi: 10.1007/s10877-015-9725-4. Epub 2015 Jun 19.
This study was to investigate and define what is considered as a current clinical practice in hemodynamic monitoring and vasoactive medication use after cardiac surgery in Italy. A 33-item questionnaire was sent to all intensive care units (ICUs) admitting patients after cardiac surgery. 71 out of 92 identified centers (77.2 %) returned a completed questionnaire. Electrocardiogram, invasive blood pressure, central venous pressure, pulse oximetry, diuresis, body temperature and blood gas analysis were identified as routinely used hemodynamic monitoring, whereas advanced monitoring was performed with pulmonary artery catheter or echocardiography. Crystalloids were the fluids of choice for volume replacement (86.8 % of Centers). To guide volume management, central venous pressure (26.7 %) and invasive blood pressure (19.7 %) were the most frequently used parameters. Dobutamine was the first choice for treatment of left heart dysfunction (40 %) and epinephrine was the first choice for right heart dysfunction (26.8 %). Half of the Centers had an internal protocol for vasoactive drugs administration. Intra-aortic balloon pump and extra-corporeal membrane oxygenation were widely available among Cardiothoracic ICUs. Angiotensin-converting enzyme inhibitors were suspended in 28 % of the Centers. The survey shows what is considered as standard monitoring in Italian Cardiac ICUs. Standard, routinely used monitoring consists of ECG, SpO2, etCO2, invasive BP, CVP, diuresis, body temperature, and BGA. It also shows that there is large variability among the various Centers regarding hemodynamic monitoring of fluid therapy and inotropes administration. Further research is required to better standardize and define the indicators to improve the standards of intensive care after cardiac surgery among Italian cardiac ICUs.
本研究旨在调查并确定意大利心脏手术后血流动力学监测和血管活性药物使用方面的当前临床实践情况。一份包含33个条目的问卷被发送至所有收治心脏手术后患者的重症监护病房(ICU)。在92个确认的中心中,有71个(77.2%)返回了完整的问卷。心电图、有创血压、中心静脉压、脉搏血氧饱和度、尿量、体温和血气分析被确定为常规使用的血流动力学监测手段,而高级监测则通过肺动脉导管或超声心动图进行。晶体液是容量补充的首选液体(86.8%的中心)。为指导容量管理,中心静脉压(26.7%)和有创血压(19.7%)是最常用的参数。多巴酚丁胺是治疗左心功能不全的首选药物(40%),肾上腺素是治疗右心功能不全的首选药物(26.8%)。一半的中心有血管活性药物给药的内部方案。心胸外科ICU中广泛配备了主动脉内球囊反搏和体外膜肺氧合。28%的中心停用了血管紧张素转换酶抑制剂。该调查显示了意大利心脏ICU中被视为标准监测的内容。标准的常规监测包括心电图、脉搏血氧饱和度、呼气末二氧化碳分压、有创血压、中心静脉压、尿量、体温和血气分析。调查还显示,各中心在液体治疗的血流动力学监测和强心药物给药方面存在很大差异。需要进一步研究以更好地规范和定义指标,从而提高意大利心脏ICU心脏手术后的重症监护标准。