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[急性锂中毒。持续动静脉血液滤过治疗。附病例报告]

[Acute lithium poisoning. Treatment with continuous arteriovenous hemofiltration. Apropos of a case].

作者信息

Ayuso Gatell A, León Regidor M A, Mestre Saura J, Díaz Boladeras R M, Sirvent Calvera J M, Nolla Panadés M

出版信息

Rev Clin Esp. 1989 Sep;185(4):195-7.

PMID:2608968
Abstract

We report a suicide attempt with lithium, chlorpromazine and flunitrazepam. In case of intoxication, renal excretion of lithium can be facilitated with forced diuresis by the administration of large volumes of saline solution, peritoneal dialysis or hemodialysis. In the case of our patient, treatment with saline solution was not effective, so continuous arteriovenous hemofiltration (CAVH) was performed achieving a decrease in serum lithium and obtaining a prompt clinical improvement. No secondary effects or serum lithium rebound effect were observed. We have not found any previous record of the use of CAVH in the treatment of acute lithium intoxication.

摘要

我们报告了一起使用锂盐、氯丙嗪和氟硝西泮的自杀未遂事件。发生中毒时,可通过大量输注生理盐水进行强制利尿、腹膜透析或血液透析来促进锂的肾脏排泄。对于我们的患者,生理盐水治疗无效,因此进行了连续性动静脉血液滤过(CAVH),血清锂水平降低,临床症状迅速改善。未观察到任何副作用或血清锂反弹效应。我们未发现之前有使用CAVH治疗急性锂中毒的记录。

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