原发性肾上腺平滑肌肉瘤：一例病例报告并文献复习
Primary adrenal leiomyosarcoma: a case report and review of literature.
作者信息
Zhou Yihong, Tang Yuxin, Tang Jin, Deng Fei, Gong Guanghui, Dai Yingbo
机构信息
Department of Urology, The Third Xiangya Hospital of Central South University Changsha 410013, P. R. China.
Department of Pathology, School of Basic Medical Science, Central South University Changsha 410013, P.R. China.
出版信息
Int J Clin Exp Pathol. 2015 Apr 1;8(4):4258-63. eCollection 2015.
Primary adrenal leiomyosarcoma (PAL) is an extremely rare mesenchymal tumors and originates from the smooth muscle wall of the central adrenal vein and its branches. Herein we report a case of a 49-year-old female suffering from PAL. Computed tomography revealed a well-circumscribed heterogeneously mass measuring 6 × 5 × 5 cm located in the left suprarenal areal, and a left laparoscopic adrenalectomy was underwent. Microscopic examination showed a hypercellular tumor with intersecting fascicled of spindled cells. Immunohistochemical staining showed that the cells were positive for desmin, smooth muscle actin (SMA), vimentin and negative for CD34, CD117, S100, Bcl-2 and Dog1. No oncological treatment underwent after surgery, and the patient had no recurrence or metastasis at 6 months postoperatively.
原发性肾上腺平滑肌肉瘤（PAL）是一种极其罕见的间叶性肿瘤，起源于肾上腺中央静脉及其分支的平滑肌壁。在此我们报告一例49岁患有PAL的女性病例。计算机断层扫描显示在左肾上腺区域有一个边界清晰的异质性肿块，大小为6×5×5厘米，遂进行了左侧腹腔镜肾上腺切除术。显微镜检查显示肿瘤细胞丰富，有梭形细胞交叉束状排列。免疫组织化学染色显示细胞结蛋白、平滑肌肌动蛋白（SMA）、波形蛋白呈阳性，而CD34、CD117、S100、Bcl-2和Dog1呈阴性。术后未进行肿瘤治疗，患者术后6个月无复发或转移。
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