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19例脊柱骨样骨瘤的临床发现及手术切除结果

Clinical Findings and Results of Surgical Resection in 19 Cases of Spinal Osteoid Osteoma.

作者信息

Etemadifar Mohammad Reza, Hadi Abdollah

机构信息

Orthopedic Surgery Department, Alzahra Educational Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

Asian Spine J. 2015 Jun;9(3):386-93. doi: 10.4184/asj.2015.9.3.386. Epub 2015 Jun 8.

DOI:10.4184/asj.2015.9.3.386
PMID:26097653
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4472586/
Abstract

STUDY DESIGN

Descriptive cases series.

PURPOSE

To evaluate clinical findings and results of conventional surgery in patients with spinal osteoid osteoma (OO).

OVERVIEW OF LITERATURE

OO is a rare benign tumor with spinal involvement rate of about 10%-20%.

METHODS

This descriptive study was conducted on 19 patients (11 males and 8 females with an average age of 19.8 years) with documented histopathological and imaging findings of OO referred to a university hospital. Neurologic symptoms and pain were scored before and after the open surgical excision. Data were analyzed by SPSS ver. 16 software using chi-square and significance level of 0.05.

RESULTS

The most common complaint was back or neck pain (84.2%) and in 68.4% spinal deformity (mostly scoliosis) shown with an average cobb angle of 21° at presentation. The sites of involvement were 35% in the lumbar, 35% in the thoracic, 25% in the cervical, and 5% in the sacrum. Lamina was the most common site (50%) of involvement with predilection for the right side (p=0.001). All patients were treated by conventional surgical excision with a complete recovery of pain and deformity. No recurrence occurred after a mean follow up of 44.5 months, but 4 of 19 cases instrumented because of induced instability. In one case there were two levels of involvement (C7-T1) simultaneously. Interestingly, 10 out of 19 of our cases belonged to a specific race (Bakhtiari).

CONCLUSIONS

Surgical intra-lesional curettage is potentially an effective method without any recurrence, which can lead to spontaneous scoliosis recovery and pain relief. Race may be a potential risk factor for spinal (OO).

摘要

研究设计

描述性病例系列。

目的

评估脊柱骨样骨瘤(OO)患者的临床发现及传统手术结果。

文献综述

骨样骨瘤是一种罕见的良性肿瘤,脊柱受累率约为10%-20%。

方法

本描述性研究对19例(11例男性和8例女性,平均年龄19.8岁)转诊至大学医院、有骨样骨瘤组织病理学和影像学记录的患者进行。在开放性手术切除前后对神经症状和疼痛进行评分。使用SPSS 16.0软件进行数据分析,采用卡方检验,显著性水平为0.05。

结果

最常见的主诉是背部或颈部疼痛(84.2%),68.4%的患者有脊柱畸形(主要为脊柱侧凸),就诊时平均科布角为21°。受累部位为腰椎35%、胸椎35%、颈椎25%、骶骨5%。椎板是最常见的受累部位(50%),右侧更易受累(p=0.001)。所有患者均接受传统手术切除,疼痛和畸形完全恢复。平均随访44.5个月后无复发,但19例中有4例因诱发不稳定而进行了内固定。1例患者同时有两个节段受累(C7-T1)。有趣的是,19例患者中有10例属于特定种族(巴赫蒂亚里族)。

结论

手术病灶内刮除术可能是一种有效的方法,无任何复发,可导致脊柱侧凸自发恢复和疼痛缓解。种族可能是脊柱骨样骨瘤的一个潜在危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ab1/4472586/e973e6610452/asj-9-386-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ab1/4472586/27112e2c0f96/asj-9-386-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ab1/4472586/00db416d383b/asj-9-386-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ab1/4472586/e973e6610452/asj-9-386-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ab1/4472586/27112e2c0f96/asj-9-386-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ab1/4472586/00db416d383b/asj-9-386-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ab1/4472586/e973e6610452/asj-9-386-g003.jpg

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