Wick Ryan R, Schultz Mark B, Zobel Justin, Holt Kathryn E
Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne and.
Department of Computing and Information Systems, University of Melbourne, Parkville, Victoria, Australia.
Bioinformatics. 2015 Oct 15;31(20):3350-2. doi: 10.1093/bioinformatics/btv383. Epub 2015 Jun 22.
Although de novo assembly graphs contain assembled contigs (nodes), the connections between those contigs (edges) are difficult for users to access. Bandage (a Bioinformatics Application for Navigating De novo Assembly Graphs Easily) is a tool for visualizing assembly graphs with connections. Users can zoom in to specific areas of the graph and interact with it by moving nodes, adding labels, changing colors and extracting sequences. BLAST searches can be performed within the Bandage graphical user interface and the hits are displayed as highlights in the graph. By displaying connections between contigs, Bandage presents new possibilities for analyzing de novo assemblies that are not possible through investigation of contigs alone.
Source code and binaries are freely available at https://github.com/rrwick/Bandage. Bandage is implemented in C++ and supported on Linux, OS X and Windows. A full feature list and screenshots are available at http://rrwick.github.io/Bandage.
Supplementary data are available at Bioinformatics online.
尽管从头组装图包含已组装的重叠群（节点），但用户很难访问这些重叠群之间的连接（边）。Bandage（一个用于轻松浏览从头组装图的生物信息学应用程序）是一个用于可视化带有连接的组装图的工具。用户可以放大图的特定区域，并通过移动节点、添加标签、更改颜色和提取序列与图进行交互。可以在Bandage图形用户界面内执行BLAST搜索，搜索结果会在图中显示为突出显示。通过显示重叠群之间的连接，Bandage为分析从头组装提供了新的可能性，而仅通过研究重叠群是无法实现这些可能性的。
源代码和二进制文件可在https://github.com/rrwick/Bandage免费获取。Bandage用C++实现，支持Linux、OS X和Windows系统。完整的功能列表和屏幕截图可在http://rrwick.github.io/Bandage获取。
补充数据可在《生物信息学》在线获取。
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