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髋关节表面置换术中对干骺端柄部进行骨水泥固定有长期益处吗?

Are There Long-term Benefits to Cementing the Metaphyseal Stem in Hip Resurfacing?

作者信息

Amstutz Harlan C, Le Duff Michel J, Bhaurla Sandeep K

机构信息

Joint Replacement Institute, St. Vincent Medical Center, 2200 West Third Street, Suite 400, Los Angeles, CA, 90057, USA,

出版信息

Clin Orthop Relat Res. 2015 Oct;473(10):3197-203. doi: 10.1007/s11999-015-4402-y. Epub 2015 Jun 23.

Abstract

BACKGROUND

Cementing the metaphyseal stem during hip resurfacing surgery improves the initial fixation of the femoral component. However, there may be long-term detrimental effects such as stress shielding or an increased risk of thermal necrosis associated with this technique.

QUESTIONS/PURPOSES: We compared (1) long-term survivorship free from radiographic femoral failure, (2) validated pain scores, and (3) radiographic evidence of component fixation between hips resurfaced with a cemented metaphyseal stem and hips resurfaced with the metaphyseal stem left uncemented.

METHODS

We retrospectively selected all the patients who had undergone bilateral hip resurfacing with an uncemented metaphyseal stem on one side, a cemented metaphyseal stem on the other side, and had both surgeries performed between July 1998 and February 2005. Forty-three patients matched these inclusion criteria. During that period, the indications for cementing the stem evolved in the practice of the senior author (HCA), passing through four phases; initially, only hips with large femoral defects had a cemented stem, then all stems were cemented, then all stems were left uncemented. Finally, stems were cemented for patients receiving small femoral components (< 48 mm) or having large femoral defects (or both). Of the 43 cemented stems, two, 13, 0, and 28 came from each of those four periods. All 43 patients had complete followup at a minimum of 9 years (mean, 143 ± 21 months for the uncemented stems; and 135 ± 22 months for the cemented stems; p = 0.088). Survivorship analyses were performed with Kaplan-Meier and Cox proportional hazards ratios using radiographic failure of the femoral component as the endpoint. Pain was assessed with University of California Los Angeles (UCLA) pain scores, and radiographic femoral failure was defined as complete radiolucency around the metaphyseal stem or gross migration of the femoral component.

RESULTS

There were four failures of the femoral component in the press-fit stem group while the cemented stem group had no femoral failures (p = 0.0471). With the numbers available, we found no differences between the two groups regarding pain relief or radiographic appearance other than in patients whose components developed loosening.

CONCLUSIONS

Cementing the metaphyseal stem improves long-term implant survival and does not alter long-term pain relief or the radiographic appearance of the proximal femur as had been a concern based on the results of finite element studies. We believe that patients with small component sizes and large femoral head defects have more to gain from the use of this technique which adds surface area for fixation, and there is no clinical downside to cementing the stem in patients with large component sizes.

LEVEL OF EVIDENCE

Level III, therapeutic study.

摘要

背景

在髋关节表面置换手术中,对干骺端柄进行骨水泥固定可改善股骨假体的初始固定。然而,该技术可能存在长期的有害影响,如应力遮挡或热坏死风险增加。

问题/目的:我们比较了(1)无股骨影像学失败的长期生存率,(2)有效疼痛评分,以及(3)使用骨水泥固定干骺端柄进行表面置换的髋关节与未使用骨水泥固定干骺端柄进行表面置换的髋关节之间假体固定的影像学证据。

方法

我们回顾性选择了所有在1998年7月至2005年2月期间接受双侧髋关节表面置换手术的患者,一侧使用非骨水泥固定的干骺端柄,另一侧使用骨水泥固定的干骺端柄。43名患者符合这些纳入标准。在此期间,资深作者(HCA)的手术中,骨水泥固定柄的适应证经历了四个阶段;最初,只有股骨大缺损的髋关节使用骨水泥固定柄,然后所有柄都进行骨水泥固定,之后所有柄都不进行骨水泥固定。最后,对于接受小尺寸股骨假体(<48 mm)或有大股骨缺损(或两者皆有)的患者,柄进行骨水泥固定。在43个骨水泥固定柄中,分别有2个、13个、0个和28个来自这四个时期。所有43名患者均至少有9年的完整随访(非骨水泥固定柄平均为143±21个月;骨水泥固定柄平均为135±22个月;p = 0.088)。采用Kaplan-Meier法和Cox比例风险比进行生存分析,以股骨假体的影像学失败为终点。使用加利福尼亚大学洛杉矶分校(UCLA)疼痛评分评估疼痛,股骨影像学失败定义为干骺端柄周围完全透亮或股骨假体严重移位。

结果

压配柄组有4个股骨假体失败,而骨水泥固定柄组无股骨假体失败(p = 0.0471)。就现有数据而言,我们发现两组在疼痛缓解或影像学表现方面没有差异,除非假体出现松动。

结论

对干骺端柄进行骨水泥固定可提高假体的长期生存率,并且不会改变长期疼痛缓解情况或股骨近端的影像学表现,而有限元研究结果曾对此表示担忧。我们认为,对于小尺寸假体和大股骨头缺损的患者,使用该技术可获得更多益处,因为它增加了固定表面积,并且对于大尺寸假体的患者,骨水泥固定柄在临床上没有不利影响。

证据水平

III级,治疗性研究。

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