入住内科和心脏科病房的心脏病患者的膳食补充剂消费情况。

Dietary supplement consumption among cardiac patients admitted to internal medicine and cardiac wards.

作者信息

Karny-Rahkovich Orith, Blatt Alex, Elbaz-Greener Gabby Atalya, Ziv-Baran Tomer, Golik Ahuva, Berkovitch Matityahu

机构信息

Internal Medicine B, Assaf Harofeh Medical Center, Zerifin, affiliated to the Sackler School of Medicine, Tel-Aviv University, Israel.

出版信息

Cardiol J. 2015;22(5):510-8. doi: 10.5603/CJ.a2015.0039. Epub 2015 Jun 23.

DOI:10.5603/CJ.a2015.0039

PMID:26100832

Abstract

BACKGROUND

Dietary supplements may have adverse effects and potentially interact with conventional medications. They are perceived as "natural" products, free of side effects with no need for medical consultation. Little is known about consumption of dietary supplements by patients with cardiac diseases. The objective of this study was to investigate dietary supplement consumption among cardiac patients admitted to internal and cardiology wards. Potential drug-dietary supplement interactions were also assessed.

METHODS

During a period of 6 months, patients with cardiac disease hospitalized in the Internal Medicine and Cardiology Wards at Assaf Harofeh Medical Center were evaluated regarding their dietary supplement consumption. A literature survey examining possible drug-supplement interaction was performed.

RESULTS

Out of 149 cardiac patients, 45% were dietary supplement consumers. Patients ad-mitted to the Internal Medicine Wards consumed more dietary supplements than those admit-ted to the Cardiology Division. Dietary supplement consumption was associated with older age (OR = 1.05, p = 0.022), female gender (OR = 2.94, p = 0.014) and routine physical activity (OR = 3.15, p = 0.007). Diabetes mellitus (OR = 2.68, p = 0.020), hematological diseases (OR = 13.29, p = 0.022), and the use of anti-diabetic medications (OR = 4.28, p = 0.001) were independently associated with dietary supplement intake. Sixteen potential moderate interactions between prescribed medications and dietary supplements were found.

CONCLUSIONS

Consumption of dietary supplements is common among cardiac patients. It is more common in those admitted to Internal Medicine Departments than in those admitted to the Cardiology Wards. Due to the risk of various drug-supplement interactions consumed by patients with cardiac diseases, there is a need to increase awareness and knowledge among medical staff regarding the intake of dietary supplements.

摘要

背景

膳食补充剂可能有不良影响，并可能与传统药物相互作用。它们被视为“天然”产品，无副作用且无需医疗咨询。关于心脏病患者使用膳食补充剂的情况知之甚少。本研究的目的是调查内科和心脏病科病房收治的心脏病患者的膳食补充剂使用情况。还评估了潜在的药物与膳食补充剂的相互作用。

方法

在6个月的时间里，对阿萨夫·哈罗费医疗中心内科和心脏病科病房住院的心脏病患者的膳食补充剂使用情况进行了评估。进行了一项文献调查，以研究可能的药物与补充剂的相互作用。

结果

在149名心脏病患者中，45%使用膳食补充剂。内科病房收治的患者比心脏病科收治的患者使用更多的膳食补充剂。膳食补充剂的使用与年龄较大（OR = 1.05，p = 0.022）、女性（OR = 2.94，p = 0.014）和日常体育活动（OR = 3.15，p = 0.007）有关。糖尿病（OR = 2.68，p = 0.020）、血液系统疾病（OR = 13.29，p = 0.022）以及使用抗糖尿病药物（OR = 4.28，p = 0.001）与膳食补充剂的摄入独立相关。发现了16种处方药物与膳食补充剂之间潜在的中度相互作用。