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使用心输出量监测指导围手术期血流动力学治疗。

Using cardiac output monitoring to guide perioperative haemodynamic therapy.

作者信息

McGuinness Shay, Parke Rachael

机构信息

aCardiothoracic and Vascular ICU, Auckland City Hospital, Auckland bMedical Research Institute of New Zealand, Wellington, New Zealand cAustralia and New Zealand Intensive Care Research Centre, School of Epidemiology and Public Health, Monash University, Melbourne, Australia dFaculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.

出版信息

Curr Opin Crit Care. 2015 Aug;21(4):364-8. doi: 10.1097/MCC.0000000000000212.

Abstract

PURPOSE OF REVIEW

The aim of this study was to review recent advances and evidence for the use of cardiac output monitors to guide perioperative haemodynamic therapy.

RECENT FINDINGS

There are multiple different cardiac output monitoring devices available for clinical use which are coupled with many different intervention protocols to manipulate perioperative haemodynamics. There is little evidence to demonstrate superiority of any one device. Previous small studies and meta-analyses have suggested that perioperative haemodynamic therapy guided by cardiac output monitoring improves outcomes after major surgery. Despite relatively low-quality evidence several national bodies have recommended 'perioperative goal-directed therapy' (GDT) as a standard of care.Recent larger trials of GDT have mostly failed to prove a benefit of GDT and one explanation for this is the increased quality of usual care that may be occurring because of initiatives such as enhanced recovery after surgery and the WHO Safer Surgery programmes.

SUMMARY

Perioperative GDT remains an exciting intervention to reduce significant morbidity following major surgery; however, it is not yet a proven standard of care. Further large pragmatic trials are required to demonstrate its effectiveness particularly in the era of enhanced recovery after surgery programmes.

摘要

综述目的

本研究旨在回顾使用心输出量监测仪指导围手术期血流动力学治疗的最新进展和证据。

最新发现

有多种不同的心输出量监测设备可供临床使用,这些设备与许多不同的干预方案相结合,以控制围手术期血流动力学。几乎没有证据表明任何一种设备具有优越性。先前的小型研究和荟萃分析表明,心输出量监测指导下的围手术期血流动力学治疗可改善大手术后的结局。尽管证据质量相对较低,但几个国家机构已推荐“围手术期目标导向治疗”(GDT)作为一种护理标准。最近关于GDT的大型试验大多未能证明GDT的益处,对此的一种解释是,由于诸如术后加速康复和世界卫生组织更安全手术计划等举措,常规护理质量可能有所提高。

总结

围手术期GDT仍然是一种令人兴奋的干预措施,可降低大手术后的严重发病率;然而,它尚未成为一种经过验证的护理标准。需要进一步的大型实用性试验来证明其有效性,尤其是在术后加速康复计划的时代。

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