Bezuska Laurynas, Lebetkevicius Virgilijus, Lankutis Kestutis, Sudikiene Rita, Sirvydis Vytautas Jonas, Tarutis Virgilijus
Department of Cardiovascular Medicine, Vilnius University, Santariskiu 2, 08661, Vilnius, Lithuania.
Centre of Cardiac Surgery, Vilnius University Hospital Santariskiu Klinikos, Santariskiu 2, 08661, Vilnius, Lithuania.
Pediatr Cardiol. 2015 Dec;36(8):1680-4. doi: 10.1007/s00246-015-1217-2. Epub 2015 Jun 24.
Most single ventricle patients undergo Fontan procedure earlier in current era. However, optimal timing of Fontan completion after an intermediate staging surgery is controversial. We present children who had Fontan surgeries younger than 3 years of age comparing the data with older patients. Between 2000 and 2013, 45 patients with functional single ventricle underwent extracardiac total cavopulmonary connection (TCPC) using GORE-TEX(®) conduit at a single institution. Children were divided into group A (age < 36 months; n = 15) and group B (age ≥ 36 months; n = 30), and retrospectively reviewed. Median follow-up was 2.9 [interquartile range (IQR) 2-4.4] years. There were two hospital deaths and one late death (all in group B, p = 0.286). One TCPC was taken down in group A. The median intensive care unit and hospital stay were 90 (IQR 46-140) h and 21 (IQR 16-33) days for group A versus 65 (IQR 45-115) h and 29 (IQR 20.8-38.5) days for group B, respectively (p = 0.322 and p = 0.057). Ventricular ejection fraction and GORE-TEX(®) conduit size were similar in both groups. The time of chest drain stay was significantly lower in group A (median 12 days, IQR 7-22) than in group B (22 days, IQR 16-32.5) (p = 0.014). Extracardiac TCPC can be performed earlier with good intermediate results. Earlier Fontan procedure might be advantageous for reducing chest drains stay.
在当今时代,大多数单心室患者更早地接受了Fontan手术。然而,在进行中间分期手术后完成Fontan手术的最佳时机仍存在争议。我们展示了年龄小于3岁接受Fontan手术的儿童,并将数据与年龄较大的患者进行比较。2000年至2013年期间,45例功能性单心室患者在同一机构使用GORE-TEX(®)导管进行了心外全腔静脉肺动脉连接(TCPC)。儿童被分为A组(年龄<36个月;n = 15)和B组(年龄≥36个月;n = 30),并进行回顾性分析。中位随访时间为2.9[四分位间距(IQR)2 - 4.4]年。有2例住院死亡和1例晚期死亡(均在B组,p = 0.286)。A组有1例TCPC被拆除。A组的中位重症监护病房和住院时间分别为90(IQR 46 - 140)小时和21(IQR 16 - 33)天,而B组分别为65(IQR 45 - 115)小时和29(IQR 20.8 - 38.5)天(p = 0.322和p = 0.057)。两组的心室射血分数和GORE-TEX(®)导管尺寸相似。A组的胸腔引流停留时间明显低于B组(中位12天,IQR 7 - 22)(22天,IQR 16 - 32.5)(p = 0.014)。心外TCPC可以更早进行,且中期结果良好。更早进行Fontan手术可能有利于减少胸腔引流停留时间。