Cassidy L F, Patterson J L
Division of Infectious Diseases, Children's Hospital, Boston, Massachusetts.
Antimicrob Agents Chemother. 1989 Nov;33(11):2009-11. doi: 10.1128/AAC.33.11.2009.
The effect of ribavirin on the growth and replication of La Crosse virus was examined. The data suggest that low concentrations of ribavirin have a marked effect on the initial steps of La Crosse virus transcription. The therapeutic potential of ribavirin in the treatment of human California encephalitis serotype infections is discussed in light of these findings.
研究了利巴韦林对拉科罗斯病毒生长和复制的影响。数据表明,低浓度的利巴韦林对拉科罗斯病毒转录的起始步骤有显著影响。根据这些发现,讨论了利巴韦林在治疗人类加利福尼亚脑炎血清型感染中的治疗潜力。