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Pilon骨折手术部位感染的危险因素。

Risk factors for surgical site infection of pilon fractures.

作者信息

Ren Tingting, Ding Liang, Xue Feng, He Zhimin, Xiao Haijun

机构信息

Department of Intensive Care Unit South Campus, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China.

Department of Orthopaedics, Shanghai Fengxian Central Hospital, Shanghai, China.

出版信息

Clinics (Sao Paulo). 2015 Jun;70(6):419-22. doi: 10.6061/clinics/2015(06)06. Epub 2015 Jun 1.

Abstract

OBJECTIVES

Pilon fracture is a complex injury that is often associated with severe soft tissue damage and high rates of surgical site infection. The goal of this study was to analyze and identify independent risk factors for surgical site infection among patients undergoing surgical fixation of a pilon fracture.

METHODS

The medical records of all pilon fracture patients who underwent surgical fixation from January 2010 to October 2012 were reviewed to identify those who developed a surgical site infection. Then, we constructed univariate and multivariate logistic regressions to evaluate the independent associations of potential risk factors with surgical site infection in patients undergoing surgical fixation of a pilon fracture.

RESULTS

A total of 519 patients were enrolled in the study from January 2010 to October 2012. A total of 12 of the 519 patients developed a surgical site infection, for an incidence of 2.3%. These patients were followed for 12 to 29 months, with an average follow-up period of 19.1 months. In the final regression model, open fracture, elevated postoperative glucose levels (≥125 mg/dL), and a surgery duration of more than 150 minutes were significant risk factors for surgical site infection following surgical fixation of a pilon fracture.

CONCLUSIONS

Open fractures, elevated postoperative glucose levels (≥125 mg/dL), and a surgery duration of more than 150 minutes were related to an increased risk for surgical site infection following surgical fixation of a pilon fracture. Patients exhibiting the risk factors identified in this study should be counseled regarding the possible surgical site infection that may develop after surgical fixation.

摘要

目的

Pilon骨折是一种复杂的损伤,常伴有严重的软组织损伤和较高的手术部位感染率。本研究的目的是分析和确定接受Pilon骨折手术固定的患者发生手术部位感染的独立危险因素。

方法

回顾2010年1月至2012年10月期间所有接受手术固定的Pilon骨折患者的病历,以确定发生手术部位感染的患者。然后,我们构建单因素和多因素逻辑回归模型,以评估潜在危险因素与接受Pilon骨折手术固定患者手术部位感染的独立相关性。

结果

2010年1月至2012年10月共有519例患者纳入本研究。519例患者中共有12例发生手术部位感染,发生率为2.3%。这些患者随访12至29个月,平均随访时间为19.1个月。在最终回归模型中,开放性骨折、术后血糖水平升高(≥125 mg/dL)以及手术时间超过150分钟是Pilon骨折手术固定后手术部位感染的显著危险因素。

结论

开放性骨折、术后血糖水平升高(≥125 mg/dL)以及手术时间超过150分钟与Pilon骨折手术固定后手术部位感染风险增加有关。应向表现出本研究中确定的危险因素的患者告知手术固定后可能发生的手术部位感染情况。

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