Porwal Harshit, Estili Mehdi, Grünewald Alina, Grasso Salvatore, Detsch Rainer, Hu Chunfeng, Sakka Yoshio, Boccaccini Aldo R, Reece Mike J
School of Engineering and Material Science, Queen Mary University of London, London, E1 4NS, UK.
J Mater Sci Mater Med. 2015 Jun;26(6):199. doi: 10.1007/s10856-015-5529-9. Epub 2015 Jun 25.
Multi-walled carbon nanotube (MWCNT)-Bioglass (BG) matrix composite was fabricated using a facile and scalable aqueous colloidal processing method without using any surfactants followed by spark plasma sintering (SPS) consolidation. The individual MWCNTs were initially uniformly dispersed in water and then entirely immobilized on the BG particles during the colloidal processing, avoiding their common re-agglomeration during the water-removal and drying step, which guaranteed their uniform dispersion within the dense BG matrix after the consolidation process. SPS was used as a fast sintering technique to minimise any damage to the MWCNT structure during the high-temperature consolidation process. The electrical conductivity of BG increased by 8 orders of magnitude with the addition of 6.35 wt% of MWCNTs compared to pure BG. Short-duration tests were used in the present study as a preliminary evaluation to understand the effect of incorporating MWCNTs on osteoblast-like cells. The analysed cell proliferation, viability and phenotype expression of MG-63 cells showed inhibition on 45S5 Bioglass(®)-MWCNT composite surfaces.
采用简便且可扩展的水性胶体加工方法,在不使用任何表面活性剂的情况下制备了多壁碳纳米管(MWCNT)-生物玻璃(BG)基复合材料,随后进行放电等离子烧结(SPS)固结。最初,单个MWCNT均匀分散在水中,然后在胶体加工过程中完全固定在BG颗粒上,避免了它们在脱水和干燥步骤中常见的重新团聚,这确保了它们在固结过程后在致密的BG基质中均匀分散。SPS被用作一种快速烧结技术,以在高温固结过程中使对MWCNT结构的任何损害最小化。与纯BG相比,添加6.35 wt%的MWCNTs后,BG的电导率提高了8个数量级。在本研究中,采用短期试验作为初步评估,以了解掺入MWCNTs对成骨样细胞的影响。对MG-63细胞的细胞增殖、活力和表型表达的分析表明,在45S5生物玻璃(®)-MWCNT复合表面上受到了抑制。