Koukoura Ourania, Klados George, Strataki Maria, Daponte Alexandros
Obstetrics and Gynaecology Department, University Hospital of Larissa, Larissa, Greece.
Pathology Department, University Hospital of Larissa, Thessaly, Larissa, Greece.
BMJ Case Rep. 2015 Jun 24;2015:bcr2014208126. doi: 10.1136/bcr-2014-208126.
A young woman presented to the outpatient gynaecology clinic with a rapidly growing bulky tumour located at the external genitalia, which she first noticed 10 days prior to her visit. Examination revealed a 6 × 3 cm cauliflower-like mass located on the left genitofemoral fold. The initial biopsy had several features suggestive of a human papilloma virus (HPV) infection. A broad excision of the mass was subsequently performed. The biopsy confirmed the presence of a large condyloma acuminatum. Condyloma acuminatum is a slow-growing benign exophytic tumour that is associated with HPV infection. In cases where the tumour has aggressive features, as in our patient, the differential diagnosis has to include carcinoma or Buschke-Löwenstein tumour. The initial biopsy of the tumour in our patient, however, excluded malignancy.
一名年轻女性因外生殖器处有一个迅速生长的巨大肿瘤前来妇科门诊就诊,她在就诊前10天首次发现该肿瘤。检查发现左侧股股沟皱襞处有一个6×3厘米的菜花状肿物。最初的活检有多项特征提示人乳头瘤病毒(HPV)感染。随后对肿物进行了广泛切除。活检证实为巨大尖锐湿疣。尖锐湿疣是一种生长缓慢的良性外生性肿瘤,与HPV感染有关。在肿瘤具有侵袭性特征的病例中,如我们的患者,鉴别诊断必须包括癌或Buschke-Löwenstein肿瘤。然而,我们患者肿瘤的最初活检排除了恶性肿瘤。