Safavi-Naeini Payam, Razavi Mehdi, Saeed Mohammad, Rasekh Abdi, Massumi Ali
Department of Cardiology, Texas Heart Institute, Houston, Texas, USA.
J Tehran Heart Cent. 2015 Apr 3;10(2):69-73.
The prevalence of atrial fibrillation (AF) is 1-2 % in the general population, and the risk of embolic stroke in AF patients is 4-5 times higher than that in the general population. AF-related strokes are often severe, and the rate of permanent disability is much higher among individuals who have AF-related strokes than in those who have strokes unrelated to AF. In patients with AF, more than 90 % of thrombi originate from the left atrial appendage (LAA). The purpose of this paper is to review the efficacy and safety of performing the LAA closure with the LARIAT Suture Delivery Device to prevent AF-related stroke in patients with contraindications to oral anticoagulant therapy.
心房颤动(AF)在普通人群中的患病率为1%-2%,AF患者发生栓塞性卒中的风险比普通人群高4-5倍。AF相关的卒中通常较为严重,与AF相关卒中的患者永久性残疾率远高于非AF相关卒中的患者。在AF患者中,超过90%的血栓起源于左心耳(LAA)。本文旨在综述使用LARIAT缝线输送装置进行LAA封堵以预防口服抗凝治疗禁忌的AF患者发生AF相关卒中的有效性和安全性。