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高频超声在银屑病关节炎评估中的临床研究

High-Frequency Ultrasound in the Evaluation of Psoriatic Arthritis: A Clinical Study.

作者信息

Lin Zhiguo, Wang Yu, Mei Yifang, Zhao Yanping, Zhang Zhiyi

机构信息

Department of Rheumatology, First Affiliated Hospital of Harbin Medical University, Harbin, China.

出版信息

Am J Med Sci. 2015 Jul;350(1):42-6. doi: 10.1097/MAJ.0000000000000504.

Abstract

BACKGROUND

This study aimed to compare high-frequency ultrasound (HFU) findings in the fingers with psoriatic arthritis (PsA) and rheumatoid arthritis (RA) and to explore the potential use of HFU in the early diagnosis of PsA.

METHODS

Forty-four PsA patients with 123 fingers with symptoms, 39 RA patients with 122 fingers with symptoms and 20 healthy patients were recruited as controls. The ultrasound imaging manifestation and blood flow of fingers were recorded and compared. The results were analyzed by the χ test.

RESULTS

Abnormal ultrasound findings in the fingers of RA and PsA patients were identified and compared. Among RA patients, 82 (67.21%) were diagnosed with joint effusion, 78 (63.93%) were synovial thickening and 59 (48.36%) were bone erosion, while no tenosynovitis, soft tissue inflammation or enthesitis was found. However, among the patients with PsA, 75 (60.97%) were diagnosed with joint effusion, 68 (55.28%) were synovial thickening, 71 (57.72%) were bone erosion, 71 (57.72%) were tenosynovitis, 44 (35.77%) were soft tissue inflammation and 39 (31.70%) were enthesitis.

CONCLUSIONS

HFU proved valuable in detecting soft tissue inflammation and enthesitis in the fingers of PsA patients. HFU may be an easy, safe and effective examination in the early diagnosis of PsA and observation of pathological changes of PsA.

摘要

背景

本研究旨在比较银屑病关节炎(PsA)和类风湿关节炎(RA)患者手指的高频超声(HFU)表现,并探讨HFU在PsA早期诊断中的潜在应用。

方法

招募44例有手指症状的PsA患者、39例有手指症状的RA患者以及20例健康患者作为对照。记录并比较手指的超声成像表现和血流情况。结果采用χ检验进行分析。

结果

对RA和PsA患者手指的超声异常表现进行了识别和比较。在RA患者中,82例(67.21%)被诊断为关节积液,78例(63.93%)为滑膜增厚,59例(48.36%)为骨侵蚀,未发现腱鞘炎、软组织炎症或附着点炎。然而,在PsA患者中,75例(60.97%)被诊断为关节积液,68例(55.28%)为滑膜增厚,71例(57.72%)为骨侵蚀,71例(57.72%)为腱鞘炎,44例(35.77%)为软组织炎症,39例(31.70%)为附着点炎。

结论

HFU被证明在检测PsA患者手指的软组织炎症和附着点炎方面具有价值。HFU可能是PsA早期诊断及观察PsA病理变化的一种简便、安全且有效的检查方法。

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