先进神经影像学技术在脑转移瘤中的新作用。

The emerging role of advanced neuroimaging techniques for brain metastases.

作者信息

Nowosielski Martha, Radbruch Alexander

机构信息

Department of Neurology, Medical University Innsbruck, Anichstrasse 35, A-6020 Innsbruck, Austria.

Department of Neuroradiology, University of Heidelberg Medical Center, Heidelberg, Germany; Department of Radiology, DKFZ, Heidelberg, Germany.

出版信息

Chin Clin Oncol. 2015 Jun;4(2):23. doi: 10.3978/j.issn.2304-3865.2015.05.04.

DOI:10.3978/j.issn.2304-3865.2015.05.04

PMID:26112809

Abstract

Brain metastases are an increasingly encountered and frightening manifestation of systemic cancer. More effective therapeutic strategies for the primary tumor are resulting in longer patient survival on the one hand while on the other, better brain tumor detection has resulted from increased availability and development of more precise brain imaging methods. This review focuses on the emerging role of functional neuroimaging techniques; magnetic resonance imaging (MRI) as well as positron emission tomography (PET), in establishing diagnosis, for monitoring treatment response with an emphasis on new targeted as well as immunomodulatory therapies and for predicting prognosis in patients with brain metastases.

摘要

脑转移是系统性癌症中越来越常见且令人恐惧的一种表现。一方面，针对原发肿瘤更有效的治疗策略使患者生存期延长；另一方面，更精确的脑成像方法的更多应用及发展，使得脑肿瘤检测更为精准。本综述重点关注功能神经成像技术（磁共振成像（MRI）以及正电子发射断层扫描（PET））在脑转移患者的诊断确立、治疗反应监测（重点是新的靶向治疗以及免疫调节治疗）和预后预测方面的新作用。