用于内窥镜光学相干断层扫描的小型化磁驱动扫描探头。
Miniaturized magnetic-driven scanning probe for endoscopic optical coherence tomography.
作者信息
Pang Ziwei, Wu Jigang
机构信息
Biophotonics Lab, University of Michigan-Shanghai Jiao Tong University Joint Institute, Shanghai Jiao Tong University, Shanghai, 200240, China.
Biophotonics Lab, University of Michigan-Shanghai Jiao Tong University Joint Institute, Shanghai Jiao Tong University, Shanghai, 200240, China ; State Key Laboratory of Low-Dimension Quantum Physics, Tsinghua University, Beijing, 100084, China.
出版信息
Biomed Opt Express. 2015 May 26;6(6):2231-6. doi: 10.1364/BOE.6.002231. eCollection 2015 Jun 1.
We designed and implemented a magnetic-driven scanning (MDS) probe for endoscopic optical coherence tomography (OCT). The probe uses an externally-driven tiny magnet in the distal end to achieve unobstructed 360-degree circumferential scanning at the side of the probe. The design simplifies the scanning part inside the probe and thus allows for easy miniaturization and cost reduction. We made a prototype probe with an outer diameter of 1.4 mm and demonstrated its capability by acquiring OCT images of ex vivo trachea and artery samples from a pigeon. We used a spectrometer-based Fourier-domain OCT system and the system sensitivity with our prototype probe was measured to be 91 dB with an illumination power of 850 μW and A-scan exposure time of 1 ms. The axial and lateral resolutions of the system are 6.5 μm and 8.1 μm, respectively.
我们设计并实现了一种用于内镜光学相干断层扫描（OCT）的磁驱动扫描（MDS）探头。该探头在远端使用一个外部驱动的微小磁体，以在探头侧面实现无阻碍的360度圆周扫描。这种设计简化了探头内部的扫描部件，从而便于实现小型化并降低成本。我们制作了一个外径为1.4毫米的原型探头，并通过获取鸽子离体气管和动脉样本的OCT图像展示了其性能。我们使用了基于光谱仪的傅里叶域OCT系统，在照明功率为850微瓦且A扫描曝光时间为1毫秒的情况下，测得我们的原型探头的系统灵敏度为91分贝。该系统的轴向分辨率和横向分辨率分别为6.5微米和8.1微米。
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