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双角旋转扫描光学相干断层扫描前向成像探头

Paired-angle-rotation scanning optical coherence tomography forward-imaging probe.

作者信息

Wu Jigang, Conry Michael, Gu Chunhui, Wang Fei, Yaqoob Zahid, Yang Changhuei

机构信息

Department of Electrical Engineering, California Institute of Technology, California 91125, USA.

出版信息

Opt Lett. 2006 May 1;31(9):1265-7. doi: 10.1364/ol.31.001265.

Abstract

We report a novel forward-imaging optical coherence tomography (OCT), needle-probe paired-angle-rotation scanning OCT (PARS-OCT) probe. The probe uses two rotating angled gradient-index lenses to scan the output OCT probe beam over a wide angular arc (approximately 19 degrees half-angle) of the region forward of the probe. Among other advantages, this probe design is readily amenable to miniaturization and is capable of a variety of scan modes, including volumetric scans. To demonstrate the advantages of the probe design, we have constructed a prototype probe with an outer diameter of 1.65 mm and employed it to acquire four OCT images, with a 45 degrees angle between adjacent images, of the gill structure of a Xenopus laevis tadpole. The system sensitivity was measured to be 93 dB by using the prototype probe with an illumination power of 450 microW on the sample. Moreover, the axial and the lateral resolutions of the probe are 9.3 and 10.3-12.5 microm, respectively.

摘要

我们报告了一种新型的前向成像光学相干断层扫描(OCT)针式探头——针式探头配对角旋转扫描OCT(PARS-OCT)探头。该探头使用两个旋转的成角度梯度折射率透镜,在探头前方区域的宽角弧(约19度半角)上扫描输出的OCT探头光束。除其他优点外,这种探头设计易于小型化,并且能够实现多种扫描模式,包括容积扫描。为了证明探头设计的优点,我们构建了一个外径为1.65毫米的原型探头,并使用它获取了非洲爪蟾蝌蚪鳃结构的四张OCT图像,相邻图像之间的夹角为45度。通过在样品上使用照明功率为450微瓦的原型探头,测得系统灵敏度为93分贝。此外,该探头的轴向分辨率和横向分辨率分别为9.3微米和10.3 - 12.5微米。

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