Celikoglu Mevlüt, Buyuk S Kutalmiş, Sekerci A Ercan
*Department of Orthodontics, Faculty of Dentistry, Akdeniz University, Antalya †Department of Orthodontics, Faculty of Dentistry, Ordu University, Ordu ‡Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Erciyes University, Kayseri, Turkey.
J Craniofac Surg. 2015 Jul;26(5):1647-51. doi: 10.1097/SCS.0000000000001815.
The aim of the study was to evaluate the soft tissue thickness of the patients affected by unilateral cleft lip and palate (UCLP) and to compare the findings with a matched control group without cleft using cone beam computed tomography (CBCT).
The study sample consisted of 66 patients (31 women and 35 men) divided into 2 groups as UCLP group (34 patients; 23 men and 11 women; 9 right sided and 25 left sided; mean age: 14.11 ± 3.48 years) and control group (32 patients; 12 men and 20 women; mean age: 15.10 ± 3.13 years) without any cleft. Angular angle between Nasion-A line and Nasion-B line (ANB), angle between Sella-Nasion line and Gonion-Menton line (SN-MP) and linear (glabella, nasion, rhinion, subnasale, labrale superius, stomion, labrale inferius, labiomentale, pogonion, and gnathion) measurements were done using CBCT. Student t test was performed to compare the variables between the groups.
Soft tissue thickness values for men were higher in both groups, except for rhinion and glabella. Subnasale for women (P = 0.000), men (P = 0.006), and total samples (P = 0.000) and the variable of the labrale superius for men (P = 0.047) and total samples (P = 0.040) were found to be statistically significantly thinner in the UCLP group. SN-MP had significant affect on subnasale thickness (R = 15.8; Beta = -0.397; P = 0.001).
Thickness of the subnasale and the labrale superius were found to be statistically significantly thinner in the UCLP group compared with the controls.
本研究旨在利用锥形束计算机断层扫描（CBCT）评估单侧唇腭裂（UCLP）患者的软组织厚度，并将结果与无腭裂的匹配对照组进行比较。
研究样本包括66例患者（31名女性和35名男性），分为UCLP组（34例患者；23名男性和11名女性；9例右侧和25例左侧；平均年龄：14.11±3.48岁）和对照组（32例患者；12名男性和20名女性；平均年龄：15.10±3.13岁），对照组无任何腭裂。使用CBCT测量鼻根点 - A线与鼻根点 - B线之间的角（ANB）、蝶鞍 - 鼻根线与下颌角 - 颏下点线之间的角（SN - MP）以及线性测量值（眉间点、鼻根点、鼻棘点、鼻下点、上唇缘点、口裂点、下唇缘点、唇颏点、颏前点和颏下点）。进行学生t检验以比较两组之间的变量。
除鼻棘点和眉间点外，两组男性的软组织厚度值均较高。发现UCLP组女性（P = 0.000）、男性（P = 0.006）和总样本（P = 0.000）的鼻下点以及男性（P = 0.047）和总样本（P = 0.040）的上唇缘点变量在统计学上显著变薄。SN - MP对鼻下点厚度有显著影响（R = 15.8；β = -0.397；P = 0.001）。
与对照组相比，UCLP组的鼻下点和上唇缘点厚度在统计学上显著变薄。
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