Cobb Tyson K, Walden Anna L, Cao Ying
Orthopaedic Surgery, Hand and Upper Extremity Service, Orthopaedic Specialists, Inc., Davenport, IA.
Department of Research, Orthopaedic Specialists, Inc., Davenport, IA.
J Hand Surg Am. 2015 Sep;40(9):1844-51. doi: 10.1016/j.jhsa.2015.05.010. Epub 2015 Jun 26.
To report results on 144 cases following arthroscopic resection arthroplasty (ARA) with or without interposition for basal joint arthritis.
Cases undergoing ARA for thumb carpometacarpal osteoarthritis between 2004 and 2011 were prospectively enrolled (n = 178). Data were collected before surgery and after surgery at 1, 3, 6, and 12 months and annually thereafter. Patients were excluded for less than 1-year follow-up or concomitant procedures that interfered with evaluation of the variable of interest (interposition). Human acellular dermal matrix (GRAFTJACKET) was the most commonly used interposition. Outcomes on 19 cases of interposition using collagen bioimplant (OrthADAPT) and porous polyurethaneurea (Artelon) scaffolds were also reported. Comparative analyses were performed on 52 patients with GRAFTJACKET interposition and on 73 without. Mean follow-up was 7.4 and 5.6 years with and without interposition, respectively. Descriptive statistics were evaluated on all baseline variables. Raw change scores of grip, pinch, and pain outcomes were evaluated. Confounding variables at a significance level of P less than .05 were adjusted for in linear mixed models, and an analysis of covariance was employed through an unstructured type of variance-covariance matrix.
Change scores from baseline to 1 year for the interposition group for pain (numerical rating scale, 0-10), pinch, and grip was -5.8, 3.3, and 7, respectively, and -5.1, 2.1, and 9 for the noninterposition group. Postoperative mean satisfaction was 4.7 and 4.4 for the with- and without-interposition groups, respectively. There were 4 failures with and 2 without interposition. Artelon and OrthADAPT did poorly with unacceptably high failure rates.
This study suggested that interposition is not necessary following ARA for thumb basal joint arthritis. Because arthroscopic interposition of material contributes to health care costs in terms of patient and facility costs without clear benefit to the patient, routine use of expensive interposition products should be abandoned or carefully evaluated with a prospective randomized controlled trial.
TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic IV.
报告144例接受关节镜下切除关节成形术(ARA)治疗第一腕掌关节关节炎(伴或不伴植入物)的结果。
前瞻性纳入2004年至2011年间因拇指腕掌关节骨关节炎接受ARA的病例(n = 178)。在手术前、术后1、3、6和12个月以及此后每年收集数据。对随访时间不足1年或存在干扰感兴趣变量(植入物)评估的伴随手术的患者进行排除。人脱细胞真皮基质(GRAFTJACKET)是最常用的植入物。还报告了19例使用胶原蛋白生物植入物(OrthADAPT)和多孔聚氨酯脲(Artelon)支架进行植入的结果。对52例使用GRAFTJACKET植入物和73例未使用植入物的患者进行了比较分析。使用植入物和未使用植入物的患者平均随访时间分别为7.4年和5.6年。对所有基线变量进行描述性统计。评估握力、捏力和疼痛结果的原始变化分数。在显著性水平P小于0.05的情况下,对线性混合模型中的混杂变量进行调整,并通过非结构化类型的方差协方差矩阵采用协方差分析。
植入物组从基线到1年的疼痛(数字评分量表,0 - 10)、捏力和握力变化分数分别为 -5.8、3.3和7,未植入物组分别为 -5.1、2.1和9。植入物组和未植入物组术后平均满意度分别为4.7和4.4。植入物组有4例失败,未植入物组有2例失败。Artelon和OrthADAPT效果不佳,失败率高得令人无法接受。
本研究表明,对于拇指第一腕掌关节关节炎,ARA术后无需植入物。由于关节镜下植入材料会增加患者和医疗机构的成本,且对患者无明显益处,应放弃常规使用昂贵的植入产品,或通过前瞻性随机对照试验进行仔细评估。
研究类型/证据水平:治疗性IV级。