伴有乳头瘤病及交替性颗粒层减少与颗粒层增厚的象皮病样银屑病

Elephantine Psoriasis with Papillomatosis and Alternating Hypogranulosis and Hypergranulosis.

作者信息

Koley Sankha, Mandal Rajesh Kumar, Chatterjee Kingshuk, Hassan Sk Masud, Pathak Swapan

机构信息

Department of Dermatology, B. S. Medical College, Bankura, West Bengal, India.

Department of Dermatology, Dept of North Bengal Medical College, Susrutanagar, Darjeeling, West Bengal, India.

出版信息

Indian J Dermatol. 2015 May-Jun;60(3):264-7. doi: 10.4103/0019-5154.156367.

DOI:10.4103/0019-5154.156367

PMID:26120152

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4458937/

Abstract

Psoriasis is a disease of considerable clinical and histopathological diversity. We report a rare case of elephantine psoriasis responding very well to methotrexate. Histopathology revealed abnormal papillomatosis with finger-like projections in addition to alternating orthokeratosis with overlying hypergranulosis and parakeratosis with overlying hypogranulosis. We believe that this finding may represent an odd histopathologic type in elephantine psoriasis.

摘要

银屑病是一种在临床和组织病理学上具有相当多样性的疾病。我们报告了一例罕见的象皮病样银屑病，对甲氨蝶呤反应良好。组织病理学显示除了交替出现的正角化过度伴上方颗粒层增厚和角化不全伴上方颗粒层减少外，还有异常乳头瘤样增生及指状突起。我们认为这一发现可能代表了象皮病样银屑病一种奇特的组织病理学类型。