Rogers M, McCrossin I, Commens C
Department of Dermatology, Children's Hospital, South Wales, Australia.
J Am Acad Dermatol. 1989 Mar;20(3):476-88. doi: 10.1016/s0190-9622(89)70061-x.
One hundred thirty-one patients with epidermal nevi are reviewed. The commonest site of involvement was the head and neck, and 13% of patients had widespread lesions. Ages of onset ranged from birth to 14 years. A spread beyond the original distribution was noted in 37% of patients. Many clinical patterns occurred, including eight cases of inflammatory linear verrucous epidermal nevus. A variety of other cutaneous abnormalities were found. Biopsies were performed in 41 cases. Three patients developed secondary tumors. One hundred nineteen of the patients were assessed for the presence of abnormalities in other organ systems. One or more abnormalities were demonstrated in 33% of patients, and in 5%, five or more abnormalities were detected. This study indicates that patients with epidermal nevi are at significant risk of having other abnormalities and warrant detailed initial assessment and close follow-up.
对131例表皮痣患者进行了回顾性研究。最常受累的部位是头颈部，13%的患者有广泛病变。发病年龄从出生到14岁不等。37%的患者出现了超出原始分布范围的扩散。出现了多种临床模式，包括8例炎症性线状疣状表皮痣。还发现了各种其他皮肤异常。对41例患者进行了活检。3例患者发生了继发性肿瘤。对119例患者评估了其他器官系统是否存在异常。33%的患者出现了一种或多种异常，5%的患者检测到五种或更多异常。这项研究表明，表皮痣患者有出现其他异常的显著风险，需要进行详细的初始评估和密切随访。
