Fröhlander N, Johnson O
Department of Medical Genetics, University of Umeå, Sweden.
Hum Hered. 1989;39(6):345-50. doi: 10.1159/000153886.
In patients with acute myocardial infarction, the haptoglobin (HP) groups were found to be associated with serum cholesterol levels. Heterozygotes (HP 2-1) showed serum cholesterol levels significantly higher (p less than 0.0001) than those of patients with HP 1-1 or HP 2-2. Furthermore, an association between HP type and infarction size was observed, HP 2-2 being associated with smaller infarctions.
在急性心肌梗死患者中,发现触珠蛋白(HP)类型与血清胆固醇水平有关。杂合子(HP 2-1)的血清胆固醇水平显著高于HP 1-1或HP 2-2的患者(p<0.0001)。此外,还观察到HP类型与梗死面积之间的关联,HP 2-2与较小的梗死面积相关。