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脂联素是短暂性脑缺血发作的危险因素吗?

Is adiponectin a risk factor for transient ischaemic attacks?

作者信息

Sener Ufuk, Uludag Irem Fatma, Kose Sukran, Ozcelik Murat, Zorlu Yasar

机构信息

Department of Neurology, S.B. Tepecik Training and Research Hospital, Izmir-Turkey.

出版信息

Endokrynol Pol. 2015;66(3):214-8. doi: 10.5603/EP.2015.0027.

Abstract

Adiponectin is an adipocytokine, and it plays a role in atherosclerosis. The role of adiponectin in the development of ischaemic stroke is controversial. Up to now, adiponectin was not evaluated in transient ischaemic stroke. In this study, we investigated the relationship between adiponectin and transient ischaemic attack. Forty patients with transient ischaemic attack were included into the study. In all patients, traditional risk factors of ischaemic stroke and intima-media thickness of carotid arteries were determined. Also, the relationship between these parameters and adiponectin levels were examined. No difference was found in terms of adiponectin levels between patients and healthy subjects. In addition, there was no association between adiponectin levels and traditional risk factors. Our results suggest that adiponectin may not be a predictive risk factor of transient ischaemic attack.

摘要

脂联素是一种脂肪细胞因子,在动脉粥样硬化中发挥作用。脂联素在缺血性中风发展过程中的作用存在争议。到目前为止,尚未在短暂性脑缺血发作中对脂联素进行评估。在本研究中,我们调查了脂联素与短暂性脑缺血发作之间的关系。40例短暂性脑缺血发作患者被纳入研究。对所有患者测定了缺血性中风的传统危险因素以及颈动脉内膜中层厚度。此外,还检查了这些参数与脂联素水平之间的关系。患者与健康受试者之间的脂联素水平没有差异。此外,脂联素水平与传统危险因素之间没有关联。我们的结果表明,脂联素可能不是短暂性脑缺血发作的预测性危险因素。

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