Malinova M
Akush Ginekol (Sofiia). 2015;54 Suppl 1:25-31.
Human papillomavirus (HPV) infection is the central cause of invasive cervical cancer (ICC) and its precursor lesions. Both vaccines can prevent most cases of cervical cancer. In addition, both can prevent vaginal and vulvar cancer in women, and HPV-related cancers. HPV4 can prevent genital warts in women and men. Routine vaccination of 12-year-old girls with HPV4 vaccine appears to be cost-effective in addition to providing both short-term and long-term health gains.
人乳头瘤病毒(HPV)感染是浸润性宫颈癌(ICC)及其前驱病变的主要病因。两种疫苗均可预防大多数宫颈癌病例。此外,两种疫苗还可预防女性的阴道癌和外阴癌以及与HPV相关的癌症。HPV4疫苗可预防女性和男性的尖锐湿疣。对12岁女孩常规接种HPV4疫苗除了能带来短期和长期的健康益处外,似乎还具有成本效益。